ID Q9HNB7_HALSA Unreviewed; 751 AA.
AC Q9HNB7;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=DNA binding protein eukaryotic-like {ECO:0000313|EMBL:AAG20303.1};
DE SubName: Full=Homolog to helicase {ECO:0000313|EMBL:DAC79052.1};
GN Name=dbp {ECO:0000313|EMBL:AAG20303.1};
GN OrderedLocusNames=VNG_2167G {ECO:0000313|EMBL:AAG20303.1};
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG20303.1, ECO:0000313|Proteomes:UP000000554};
RN [1] {ECO:0000313|EMBL:AAG20303.1, ECO:0000313|Proteomes:UP000000554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC {ECO:0000313|Proteomes:UP000000554}, and NRC-1
RC {ECO:0000313|EMBL:AAG20303.1};
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN [2] {ECO:0000313|EMBL:DAC79052.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC79052.1};
RX PubMed=18313895; DOI=.1016/j.ygeno.2008.01.001;
RA Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT R1 compared to that of strain NRC-1.";
RL Genomics 91:335-346(2008).
RN [3] {ECO:0000313|EMBL:DAC79052.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC79052.1};
RX PubMed=26042526;
RA Pfeiffer F., Oesterhelt D.;
RT "A manual curation strategy to improve genome annotation: application to a
RT set of haloarchael genomes.";
RL Life 5:1427-1444(2015).
RN [4] {ECO:0000313|EMBL:DAC79052.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC79052.1};
RA Pfeiffer F., Marchfelder A., Habermann B.H., Dyall-Smith M.;
RT "The genome of the Halobacterium salinarum type strain is closely related
RT to that of the laboratory strains NRC-1 and R1.";
RL Microbiol. Resour. Announc. 0:0-0(2019).
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DR EMBL; AE004437; AAG20303.1; -; Genomic_DNA.
DR EMBL; BK010829; DAC79052.1; -; Genomic_DNA.
DR PIR; C84367; C84367.
DR RefSeq; WP_010903605.1; NC_002607.1.
DR AlphaFoldDB; Q9HNB7; -.
DR STRING; 64091.VNG_2167G; -.
DR PaxDb; 64091-VNG_2167G; -.
DR GeneID; 68694734; -.
DR KEGG; hal:VNG_2167G; -.
DR PATRIC; fig|64091.14.peg.1664; -.
DR HOGENOM; CLU_370740_0_0_2; -.
DR OrthoDB; 45637at2157; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 2.40.30.270; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:DAC79052.1};
KW Hydrolase {ECO:0000313|EMBL:DAC79052.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000554}.
FT DOMAIN 346..439
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 444..511
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 524..711
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 751 AA; 80518 MW; 69E50D282C457154 CRC64;
MPDGDAPDVT PLYEAWSLHG ADRYATGDLR ARSRYLGLEH DDLRACLTQA ADVVDVPAED
GRGTVVPLHA PDTPEPTDEY VVWDPDSDAV GYFDESFGIS GAHSRVPLDD VVATAIAHRV
RFWHPARAPG GDTDPDGPLA AATVPDGVPP TDPLAGRDRR AFFDTLRETV RGERAAERDQ
TRDAHADADL RRLVDEHAVD GPFVLVSTTA HSDRPADVRV QYAPDDGAPA DIDLVAAFDL
YPDNRVLVDA FHDALPFPAR VASVDGPLVT LQPTWERVTD PEGVATTLAD ADPFWLRGLL
NPVPYTRRLD AIDAVWETPA KRRLLTGQRP LSFSRPPNRR HADLALDDHQ QRALAWAVAA
DDVACIHGPP GTGKTRTLAA VVAESVARGE RVLVTAHSNQ AVDTLLVGDS TLDAADDGSL
HGVLGDDPTV DIARHGRHSR NRVVDDHYRQ RGVDAADVVA ATTNGAATFD QNAFDLAVVD
EATQASRAAT AIAVNAADTL VLAGDHRQLP PYGVREGGAG EMRPSLFETL IDRYGDDVAV
LLARQYRMHD AIAGFPNEAF YGGRLETAAV AADRAVDGLP PVAVVDVAGQ ERRDERGASV
RNAAEASVVA DRVDTIRRAG VEPGDLGVIA AYSDHVSAIR GVLADRGLDR PALTVDTVDS
FQGGERDAVV VSFARSNDAH DAGFLEHPAA GPRRLNVALT RARRHLSLVG DWATLTDPAS
HRSPAASCAD VYADLYDTLA DHADARLFNR R
//
