ID Q9HSI4_HALSA Unreviewed; 857 AA.
AC Q9HSI4;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=SF3 helicase domain-containing protein {ECO:0000259|PROSITE:PS51206};
GN OrderedLocusNames=VNG_0215C {ECO:0000313|EMBL:AAG18822.1};
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium; Halobacterium salinarum NRC-34001.
OX NCBI_TaxID=64091 {ECO:0000313|EMBL:AAG18822.1, ECO:0000313|Proteomes:UP000000554};
RN [1] {ECO:0000313|EMBL:AAG18822.1, ECO:0000313|Proteomes:UP000000554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1
RC {ECO:0000313|Proteomes:UP000000554}, and NRC-1
RC {ECO:0000313|EMBL:AAG18822.1};
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.W., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN [2] {ECO:0000313|EMBL:DAC77507.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC77507.1};
RX PubMed=18313895; DOI=.1016/j.ygeno.2008.01.001;
RA Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT R1 compared to that of strain NRC-1.";
RL Genomics 91:335-346(2008).
RN [3] {ECO:0000313|EMBL:DAC77507.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC77507.1};
RX PubMed=26042526;
RA Pfeiffer F., Oesterhelt D.;
RT "A manual curation strategy to improve genome annotation: application to a
RT set of haloarchael genomes.";
RL Life 5:1427-1444(2015).
RN [4] {ECO:0000313|EMBL:DAC77507.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRC-1 {ECO:0000313|EMBL:DAC77507.1};
RA Pfeiffer F., Marchfelder A., Habermann B.H., Dyall-Smith M.;
RT "The genome of the Halobacterium salinarum type strain is closely related
RT to that of the laboratory strains NRC-1 and R1.";
RL Microbiol. Resour. Announc. 0:0-0(2019).
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DR EMBL; AE004437; AAG18822.1; -; Genomic_DNA.
DR EMBL; BK010829; DAC77507.1; -; Genomic_DNA.
DR PIR; B84182; B84182.
DR RefSeq; WP_010902115.1; NC_002607.1.
DR AlphaFoldDB; Q9HSI4; -.
DR STRING; 64091.VNG_0215C; -.
DR PaxDb; 64091-VNG_0215C; -.
DR GeneID; 68693184; -.
DR KEGG; hal:VNG_0215C; -.
DR PATRIC; fig|64091.14.peg.155; -.
DR HOGENOM; CLU_018483_1_1_2; -.
DR OrthoDB; 271668at2157; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006500; Helicase_put_C_phage/plasmid.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR045455; NrS-1_pol-like_helicase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR InterPro; IPR014819; PriCT_2.
DR NCBIfam; TIGR01613; primase_Cterm; 1.
DR PANTHER; PTHR35372; ATP BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR35372:SF2; SF3 HELICASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08706; D5_N; 1.
DR Pfam; PF19263; DUF5906; 1.
DR Pfam; PF08707; PriCT_2; 1.
DR SMART; SM00885; D5_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000554}.
FT DOMAIN 548..707
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
FT REGION 828..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 840..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 96057 MW; AC9435A7B94442B3 CRC64;
MSRTQTSSNG IGGKYDAIPD ELKERAQWLL WDASADTSRR PHWKDDFGIS WSDPEEWHTF
NDAVEAATER DSWGIGYVMA SENDDYPRGL YGCLDLDGCL KKSNQEKPKD WLPSLEKFIE
DGAYMEYSGS GEGIHIPFVG YEPPEWWADC QLGEHEGVDV LTNKFCAFTG NQLSVSGDSV
SGADPTQFLF EAYQEINGEA PSLSSSTGKS GDYDGDEWLD KSDIEDALSH VNPDCGYDEW
LKLGFAVHDW DSGSTGKRLF EQWSKGGSKW DNQAERNIQD IWDSASEGQG VTVGTLIHYA
KDGGWTVPTR SNPTGQSQEN GHTKPLVEAI DSSWFDLDSK TVTVQSVEGY TASELVDVFQ
KSGNILEACG HEAISAIGES DGGGEFLDDS GNGWTVEEGR KNPYAHLEPL SNQEIKNTAL
AELPTHRVAY LPKREIWLWC DDGVWKPNGD GWVRQWLDEY LGPYYSGHIR REVMDQLQAR
SQVEEQRFGG GPPGQIAAQN GLIDLDAGEI MREIQPSDHI RWTLATEYDP EADCRKWREF
LGEVVEASDI PLLQEYIGYC LRHWDVKRKK ALMLLGPTDA GKSVFVDVIE ALFGGEDSAA
TSSTSVQYLA NERWGPARLV NTALNTRSDL GKGSIENTGK VKELIAGDSL DAERKRKPVF
QFKPTAKHIF AANRAPNRSV DDEAFWNRWL TVVFPQAIPR SEQVDDLDEQ LLEELPGIFN
WAIEGYQRLE EQGHFTNQPL PYQNREKWER YGNSIAQWFD RCTEEQPDGF TPKESTDDAL
GAYDSYVAYA RQNGLEVETD SKFTSELKRR DGVSKSRRRI EGNRTYGYSG FVLTDDAPGG
SDQQEDTNRN AGIGSFE
//
