ID Q9HTS1_PSEAE Unreviewed; 458 AA.
AC Q9HTS1;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 134.
DE SubName: Full=Probable transcriptional regulator {ECO:0000313|EMBL:AAG08668.1};
GN OrderedLocusNames=PA5283 {ECO:0000313|EMBL:AAG08668.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG08668.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG08668.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; AE004091; AAG08668.1; -; Genomic_DNA.
DR PIR; G82984; G82984.
DR RefSeq; NP_253970.1; NC_002516.2.
DR RefSeq; WP_003098233.1; NZ_QZGE01000020.1.
DR AlphaFoldDB; Q9HTS1; -.
DR SMR; Q9HTS1; -.
DR PaxDb; 208964-PA5283; -.
DR GeneID; 877917; -.
DR KEGG; pae:PA5283; -.
DR PATRIC; fig|208964.12.peg.5537; -.
DR PseudoCAP; PA5283; -.
DR HOGENOM; CLU_017584_0_0_6; -.
DR InParanoid; Q9HTS1; -.
DR OrthoDB; 9802328at2; -.
DR PhylomeDB; Q9HTS1; -.
DR BioCyc; PAER208964:G1FZ6-5404-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..79
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 458 AA; 50958 MW; 7525DD513E3F98D3 CRC64;
MHLRIDRNAS EPLVQQIVAG VSGWIRGNRV RAGTRIPSIR QLARENQLSQ SSVIEAYDRL
VALGMLESRH GSGFFVAEAP AATTDLDSEW HEGAENAWGQ FSGSSTKLKL GCGWIPDSWR
EVEELSYAIR QVARSELAGL FDYSTPLGLP ALRQHIQKRL RLIDIHVDPE QILTTTGASH
ALDLLVRTLL KPGDVVVVEN PGYYNLFNLL KFHGVKMLGV PRTRHGPDTA ALETILRAHK
PKFLFTNSMY HNPTGTSLSP SVAHRVLQLA EQHDFHIVED DIYADFQNGP STRLATLDSL
RRVIYLASFS KTLSCSLRVG YLIAGPELIR RLADVKMYTS IGSQRFAECV VSTMLANGSY
RKLVQRLRQR LTRQMAATLR VLGDNGWEVF AEPVGGMFVW ARIGDYPFAE LQAVATRLDV
LLSPGSGFSP EGEESDWLRI NIAYASDPRA LAFFEAFG
//
