ID Q9HZR4_PSEAE Unreviewed; 392 AA.
AC Q9HZR4;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=Probable major facilitator superfamily (MFS) transporter {ECO:0000313|EMBL:AAG06321.1};
GN OrderedLocusNames=PA2933 {ECO:0000313|EMBL:AAG06321.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG06321.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG06321.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE004091; AAG06321.1; -; Genomic_DNA.
DR PIR; F83279; F83279.
DR RefSeq; NP_251623.1; NC_002516.2.
DR RefSeq; WP_003114005.1; NZ_QZGE01000009.1.
DR AlphaFoldDB; Q9HZR4; -.
DR SMR; Q9HZR4; -.
DR STRING; 208964.PA2933; -.
DR PaxDb; 208964-PA2933; -.
DR GeneID; 882658; -.
DR KEGG; pae:PA2933; -.
DR PATRIC; fig|208964.12.peg.3075; -.
DR PseudoCAP; PA2933; -.
DR HOGENOM; CLU_001265_61_0_6; -.
DR InParanoid; Q9HZR4; -.
DR OrthoDB; 9788453at2; -.
DR PhylomeDB; Q9HZR4; -.
DR BioCyc; PAER208964:G1FZ6-2983-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd17324; MFS_NepI_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43124; PURINE EFFLUX PUMP PBUE; 1.
DR PANTHER; PTHR43124:SF10; PURINE EFFLUX PUMP PBUE; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..380
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 392 AA; 40047 MW; 33E7E9C485EDBADE CRC64;
MLLPILLLAA AGFTILTTEF VIVGLLPALA ADLQVSVAQA GLLVSLFAFS VAAFGPFLTA
ALAGVERKRL FVACLLLFAA ANALAAVAGD IWTMAVARFV PALALPVFWA MASETAAHLA
GPSREGRAVA LVFFGIVAAT VLGIPIGTLI ADAWGWRLAF AALAALALAK ALLLAAWLPR
IPGRPGISLR SQASVLRQPL VLGHLLLSLL VFTGMFTPYT YLADILQRLA GFSGSLVGWT
LMGFGAVGLL GNWLGGRLVD RSPLGATLLF VLLMALGMLA LVPTLGNAWL LAATLATWGV
AQAALFIVGQ VRVMKSAPRA PAFAASLNIS ACNAGIGIGA LAGSRVIDGS GLAPLGEVGA
LVCLAAMAVA LLLMLAPRQA ATEPSLGGQI PH
//
