ID Q9I6W5_PSEAE Unreviewed; 221 AA.
AC Q9I6W5;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 137.
DE SubName: Full=Probable transcriptional regulator {ECO:0000313|EMBL:AAG03557.1};
GN OrderedLocusNames=PA0167 {ECO:0000313|EMBL:AAG03557.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964 {ECO:0000313|EMBL:AAG03557.1, ECO:0000313|Proteomes:UP000002438};
RN [1] {ECO:0000313|EMBL:AAG03557.1, ECO:0000313|Proteomes:UP000002438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC 1C / PRS 101 / PAO1 {ECO:0000313|Proteomes:UP000002438};
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.Q., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R., Smith K.,
RA Spencer D., Wong G.K., Wu Z., Paulsen I.T., Reizer J., Saier M.H.,
RA Hancock R.E., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
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DR EMBL; AE004091; AAG03557.1; -; Genomic_DNA.
DR PIR; E83625; E83625.
DR RefSeq; NP_248857.1; NC_002516.2.
DR RefSeq; WP_003083903.1; NZ_QZGE01000015.1.
DR AlphaFoldDB; Q9I6W5; -.
DR SMR; Q9I6W5; -.
DR STRING; 208964.PA0167; -.
DR PaxDb; 208964-PA0167; -.
DR DNASU; 879316; -.
DR GeneID; 879316; -.
DR KEGG; pae:PA0167; -.
DR PATRIC; fig|208964.12.peg.173; -.
DR PseudoCAP; PA0167; -.
DR HOGENOM; CLU_069356_1_0_6; -.
DR InParanoid; Q9I6W5; -.
DR OrthoDB; 6860332at2; -.
DR PhylomeDB; Q9I6W5; -.
DR BioCyc; PAER208964:G1FZ6-168-MONOMER; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR013573; Tscrpt_reg_YcdC_C.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF196; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR Pfam; PF08362; TetR_C_3; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000002438}.
FT DOMAIN 22..82
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 45..64
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 221 AA; 24533 MW; C0E1E1782C8A5F11 CRC64;
MTLTVPAHDP AARDKPAGRI RQKNEEAILA AAEEEFARHG FKGTSMNTIA QNVGLPKANL
HYYFGNKLGL YTAVLSNILE LWDSTFNTLG VDDDPAEALA RYIRAKMEFS RRYPLASRIF
AMEIISGGEC LTAHFNQDYR SWFRGRAAVF EAWIAAGRMD PVDPVHLIFL LWGSTQHYAD
FASQIGLVTG RKRMSRQDFA AAADNLVRII LKGCGLTPPA A
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