GenomeNet

Database: UniProt
Entry: Q9K7Q7
LinkDB: Q9K7Q7
Original site: Q9K7Q7 
ID   PCKA_BACHD              Reviewed;         527 AA.
AC   Q9K7Q7;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   26-NOV-2014, entry version 85.
DE   RecName: Full=Phosphoenolpyruvate carboxykinase [ATP] {ECO:0000255|HAMAP-Rule:MF_00453};
DE            Short=PCK {ECO:0000255|HAMAP-Rule:MF_00453};
DE            Short=PEP carboxykinase {ECO:0000255|HAMAP-Rule:MF_00453};
DE            Short=PEPCK {ECO:0000255|HAMAP-Rule:MF_00453};
DE            EC=4.1.1.49 {ECO:0000255|HAMAP-Rule:MF_00453};
GN   Name=pckA {ECO:0000255|HAMAP-Rule:MF_00453}; OrderedLocusNames=BH3302;
OS   Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM
OS   9153 / C-125).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=272558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N.,
RA   Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S.,
RA   Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus
RT   halodurans and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Involved in the gluconeogenesis. Catalyzes the
CC       conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP)
CC       through direct phosphoryl transfer between the nucleoside
CC       triphosphate and OAA. {ECO:0000255|HAMAP-Rule:MF_00453}.
CC   -!- CATALYTIC ACTIVITY: ATP + oxaloacetate = ADP + phosphoenolpyruvate
CC       + CO(2). {ECO:0000255|HAMAP-Rule:MF_00453}.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00453};
CC       Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_00453};
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00453}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00453}.
CC   -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase [ATP]
CC       family. {ECO:0000255|HAMAP-Rule:MF_00453}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; BA000004; BAB07021.1; -; Genomic_DNA.
DR   PIR; F84062; F84062.
DR   RefSeq; NP_244168.1; NC_002570.2.
DR   RefSeq; WP_010899443.1; NC_002570.2.
DR   ProteinModelPortal; Q9K7Q7; -.
DR   SMR; Q9K7Q7; 15-527.
DR   STRING; 272558.BH3302; -.
DR   EnsemblBacteria; BAB07021; BAB07021; BAB07021.
DR   GeneID; 891020; -.
DR   KEGG; bha:BH3302; -.
DR   PATRIC; 18943880; VBIBacHal18977_3439.
DR   eggNOG; COG1866; -.
DR   HOGENOM; HOG000271471; -.
DR   KO; K01610; -.
DR   OMA; GADPEHY; -.
DR   OrthoDB; EOG6DG2RK; -.
DR   BioCyc; BHAL272558:GJC5-3401-MONOMER; -.
DR   UniPathway; UPA00138; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.40.449.10; -; 1.
DR   Gene3D; 3.90.228.20; -; 2.
DR   HAMAP; MF_00453; PEPCK_ATP; 1.
DR   InterPro; IPR001272; PEP_carboxykinase_ATP.
DR   InterPro; IPR013035; PEP_carboxykinase_C.
DR   InterPro; IPR008210; PEP_carboxykinase_N.
DR   InterPro; IPR015994; PEPCK_ATP_CS.
DR   Pfam; PF01293; PEPCK_ATP; 1.
DR   PIRSF; PIRSF006294; PEP_crbxkin; 1.
DR   SUPFAM; SSF68923; SSF68923; 1.
DR   TIGRFAMs; TIGR00224; pckA; 1.
DR   PROSITE; PS00532; PEPCK_ATP; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Decarboxylase;
KW   Gluconeogenesis; Lyase; Manganese; Metal-binding; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN         1    527       Phosphoenolpyruvate carboxykinase [ATP].
FT                                /FTId=PRO_0000203807.
FT   NP_BIND     233    241       ATP. {ECO:0000255|HAMAP-Rule:MF_00453}.
FT   METAL       198    198       Manganese. {ECO:0000255|HAMAP-
FT                                Rule:MF_00453}.
FT   METAL       217    217       Manganese; via tele nitrogen.
FT                                {ECO:0000255|HAMAP-Rule:MF_00453}.
FT   METAL       254    254       Manganese. {ECO:0000255|HAMAP-
FT                                Rule:MF_00453}.
FT   BINDING      56     56       Substrate. {ECO:0000255|HAMAP-
FT                                Rule:MF_00453}.
FT   BINDING     192    192       Substrate. {ECO:0000255|HAMAP-
FT                                Rule:MF_00453}.
FT   BINDING     198    198       ATP. {ECO:0000255|HAMAP-Rule:MF_00453}.
FT   BINDING     198    198       Substrate. {ECO:0000255|HAMAP-
FT                                Rule:MF_00453}.
FT   BINDING     217    217       ATP. {ECO:0000255|HAMAP-Rule:MF_00453}.
FT   BINDING     282    282       ATP. {ECO:0000255|HAMAP-Rule:MF_00453}.
FT   BINDING     319    319       ATP. {ECO:0000255|HAMAP-Rule:MF_00453}.
FT   BINDING     319    319       Substrate. {ECO:0000255|HAMAP-
FT                                Rule:MF_00453}.
FT   BINDING     444    444       ATP. {ECO:0000255|HAMAP-Rule:MF_00453}.
SQ   SEQUENCE   527 AA;  58166 MW;  C57CDD82DC9E37B5 CRC64;
     MNTISTTTRL EQLLGDQHVL KNAPASTLVE KSLLRGEGRL TDTGALTVAT GAYTGRSPKD
     KFIVDETSVH EKIEWGQVNQ AIEKETFLHL YEKVLTYLAD KDELFEFRGF AGADKTYRLP
     LQVVNEFAWH NLFAQQLFIQ PTTEELTQHT PEFTIVSAPG FKADPSVDGT RSEAFVIISF
     EERIVLIGGT EYAGEMKKSI FSVMNYLLPE QDVLSMHCSA NVGVEGDVAL FFGLSGTGKT
     TLSADPNRKL IGDDEHGWSE RGVFNIEGGC YAKCVNLSYE KEPQIWNAIR FGSVLENVIV
     DEKTGLPDYN DTSLTENTRA AYSLEAIPNS VIPSVAGHPN TIIFLTADAF GVLPPISKLT
     PEQAMYHFLS GYTSKLAGTE RGVTSPEATF STCFGAPFLP LPAARYAEML GEKIAQYEVQ
     VFLVNTGWSG GPYGVGQRMK LSYTRAMVQA ALQGELNTVE TITDSVFGLH IPTRCPGVPD
     FVLQPRNTWD DKEKYDKKAQ ELAKQFIENF KRFTNVSEAI QKAGPSI
//
DBGET integrated database retrieval system