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Database: UniProt
Entry: Q9KIJ3
LinkDB: Q9KIJ3
Original site: Q9KIJ3 
ID   MTSA_STRMU              Reviewed;         306 AA.
AC   Q9KIJ3;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2002, sequence version 2.
DT   13-NOV-2013, entry version 92.
DE   RecName: Full=Metal ABC transporter substrate-binding lipoprotein;
DE   Flags: Precursor;
GN   Name=sloC; OrderedLocusNames=SMU_184;
OS   Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=210007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 25175 / DSM 20523 / JCM 5705 / NBRC 13955 / NCIMB 702062 /
RC   NCTC 10449;
RX   PubMed=10899841; DOI=10.1128/IAI.68.8.4441-4451.2000;
RA   Kitten T., Munro C.L., Michalek S.M., Macrina F.L.;
RT   "Genetic characterization of a Streptococcus mutans LraI family operon
RT   and role in virulence.";
RL   Infect. Immun. 68:4441-4451(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700610 / UA159;
RX   PubMed=12397186; DOI=10.1073/pnas.172501299;
RA   Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J.,
RA   Carson M.B., Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P.,
RA   Qian Y., Li S., Zhu H., Najar F.Z., Lai H., White J., Roe B.A.,
RA   Ferretti J.J.;
RT   "Genome sequence of Streptococcus mutans UA159, a cariogenic dental
RT   pathogen.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002).
CC   -!- FUNCTION: Part of an ATP-driven transport system for a metal;
CC       probably for manganese. Also act as an adhesin which is involved
CC       on adherence to extracellular matrix. It is an important factor in
CC       pathogenesis and infection. It may contribute to the formation and
CC       accumulation of dental plaque.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor (By similarity).
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 9
CC       family. Lipoprotein receptor antigen (Lrai) subfamily.
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DR   EMBL; AF232688; AAF81674.1; -; Genomic_DNA.
DR   EMBL; AE014133; AAN57959.1; -; Genomic_DNA.
DR   RefSeq; NP_720653.1; NC_004350.2.
DR   ProteinModelPortal; Q9KIJ3; -.
DR   SMR; Q9KIJ3; 25-306.
DR   STRING; 210007.SMU.184; -.
DR   EnsemblBacteria; AAN57959; AAN57959; SMU_184.
DR   GeneID; 1029755; -.
DR   KEGG; smu:SMU_184; -.
DR   PATRIC; 19662617; VBIStrMut61772_0160.
DR   eggNOG; COG0803; -.
DR   KO; K11704; -.
DR   OMA; GINTRTM; -.
DR   OrthoDB; EOG6B3601; -.
DR   ProtClustDB; CLSK876868; -.
DR   BioCyc; SMUT210007:GC7Z-189-MONOMER; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR   InterPro; IPR006129; AdhesinB.
DR   InterPro; IPR006128; Lipoprotein_4.
DR   InterPro; IPR006127; Perip_solute-bd_prot_fam.
DR   Pfam; PF01297; TroA; 1.
DR   PRINTS; PR00691; ADHESINB.
DR   PRINTS; PR00690; ADHESNFAMILY.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Complete proteome; Lipoprotein; Manganese; Membrane;
KW   Metal-binding; Palmitate; Signal; Transport; Zinc.
FT   SIGNAL        1     19       Probable.
FT   CHAIN        20    306       Metal ABC transporter substrate-binding
FT                                lipoprotein.
FT                                /FTId=PRO_0000031888.
FT   METAL        64     64       Zinc (By similarity).
FT   METAL       136    136       Zinc (By similarity).
FT   METAL       202    202       Zinc (By similarity).
FT   METAL       277    277       Zinc (By similarity).
FT   LIPID        20     20       N-palmitoyl cysteine (Probable).
FT   LIPID        20     20       S-diacylglycerol cysteine (Probable).
FT   CONFLICT    108    108       T -> A (in Ref. 1; AAF81674).
FT   CONFLICT    302    302       N -> D (in Ref. 1; AAF81674).
SQ   SEQUENCE   306 AA;  34365 MW;  CDA294394F24AB29 CRC64;
     MKKLSLLLLV CLSLLGLFAC TSKKTADKKL TVVATNSIIA DITKNIAGNK VVLHSIVPVG
     RDPHEYEPLP EDVKKTSQAD VIFYNGINLE NGGNAWFTKL VKNAHKKTDK DYFAVSDSVK
     TIYLENAKEK GKEDPHAWLD LKNGIIYAKN IMKRLSEKDP KNKSYYQKNF QAYSAKLEKL
     HKVAKEKISR IPTEKKMIVT SEGCFKYFSK AYDIPSAYIW EINTEEEGTP NQIKALVKKL
     RKSRVSALFV ESSVDDRPMK TVSKDTGIPI AAKIFTDSVA KKGQAGDSYY AMMKWNIDKI
     ANGLSQ
//
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