ID   Q9KK50_STREE            Unreviewed;       655 AA.
AC   Q9KK50;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   13-SEP-2023, entry version 75.
DE   SubName: Full=Surface protein PspC {ECO:0000313|EMBL:AAF73777.1};
GN   Name=pspC {ECO:0000313|EMBL:AAF73777.1};
OS   Streptococcus pneumoniae.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1313 {ECO:0000313|EMBL:AAF73777.1};
RN   [1] {ECO:0000313|EMBL:AAF73777.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=8R1 {ECO:0000313|EMBL:AAF73777.1};
RX   PubMed=11891047; DOI=10.1016/S0378-1119(01)00896-4;
RA   Iannelli F., Oggioni M.R., Pozzi G.;
RT   "Allelic variation in the highly polymorphic locus pspC of Streptococcus
RT   pneumoniae.";
RL   Gene 284:63-71(2002).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF154010; AAF73777.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9KK50; -.
DR   Gene3D; 1.20.81.20; -; 1.
DR   Gene3D; 2.10.270.10; Cholin Binding; 2.
DR   Gene3D; 1.20.58.440; choline binding protein A; 2.
DR   InterPro; IPR018337; Cell_wall/Cho-bd_repeat.
DR   InterPro; IPR007756; RICH.
DR   InterPro; IPR038183; RICH_sf.
DR   InterPro; IPR005877; YSIRK_signal_dom.
DR   NCBIfam; NF033838; PspC_subgroup_1; 1.
DR   NCBIfam; TIGR01168; YSIRK_signal; 1.
DR   Pfam; PF01473; Choline_bind_1; 2.
DR   Pfam; PF19127; Choline_bind_3; 2.
DR   Pfam; PF05062; RICH; 1.
DR   Pfam; PF04650; YSIRK_signal; 1.
DR   SUPFAM; SSF69360; Cell wall binding repeat; 1.
DR   PROSITE; PS51170; CW; 7.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          7..32
FT                   /note="YSIRK Gram-positive signal peptide"
FT                   /evidence="ECO:0000259|Pfam:PF04650"
FT   DOMAIN          53..135
FT                   /note="RICH"
FT                   /evidence="ECO:0000259|Pfam:PF05062"
FT   REPEAT          476..495
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REPEAT          496..515
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REPEAT          516..535
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REPEAT          536..555
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REPEAT          556..575
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REPEAT          576..595
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REPEAT          596..615
FT                   /note="Cell wall-binding"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00591"
FT   REGION          148..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          348..481
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..277
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..323
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        348..406
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..429
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..456
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        457..480
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   655 AA;  73951 MW;  30623F1EDB9D05C2 CRC64;
     MFASKSERKV HYSIRKFSIG VASVAVASLF LGGVVHAEGV GGRNTSTVTS SGQDTSKKYA
     DEVKSHYQSI LEKVRKSLEK DRHTQNVGLI TKLSEIKKKY LYELEVNVLL EEKSKAELPS
     KAKAELDAAF EQFKKEPELT KKVAEAQKKV EEAKKKAEDQ KEEDFRNYPT NTYKTIELEI
     AESDVKVKEA ELELLKEEAK EHRDEGTIKQ VEEKVKSEKA EATRLEEIKT ERKKAEEEAK
     RRADAKEQGK PKGRAKRGVP GEQATPDKKE NDAKSSDSSV GEETLPNPSL KPEKKVAEAQ
     KKVEEAKKKA KDQKEEDHRN YPTITYKTLE LEIAESDVEV KKAELELVKE EAKGSRNEEK
     VKQAKAEVES KKAEATRLEK IKTDRKKAEE AKRKAAEEDK VKEKPAEQPQ PAPAPQPEKP
     APAPKPENPA EQPKAEKPAD QQAEEDYARR SEEEYNRLTQ QQPPKTEKPA QPSTPKTGWK
     QENGMWYFYN TDGSMATGWL QNNGSWYYLN ANGSMATGWL QNNGSWYYLN ANGAMATGWL
     QNNGSWYYLN ANGDMATGWL QNNGSWYYLN ANGSMVTGWL QNNGSWYYLN ANGSMATDWV
     KDGDTWYYLE ASGAMKASQW FKVSDKWYYV NGSGALAVNT TVDSYRVNAN GEWVN
//