ID Q9KN15_VIBCH Unreviewed; 450 AA.
AC Q9KN15;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Oxidoreductase, putative {ECO:0000313|EMBL:AAF96064.1};
GN OrderedLocusNames=VC_A0151 {ECO:0000313|EMBL:AAF96064.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF96064.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF96064.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE003853; AAF96064.1; -; Genomic_DNA.
DR PIR; D82494; D82494.
DR RefSeq; NP_232551.1; NC_002506.1.
DR AlphaFoldDB; Q9KN15; -.
DR STRING; 243277.VC_A0151; -.
DR TCDB; 5.B.1.2.1; the phagocyte (gp91(phox)) nadph oxidase family.
DR DNASU; 2612539; -.
DR EnsemblBacteria; AAF96064; AAF96064; VC_A0151.
DR KEGG; vch:VC_A0151; -.
DR PATRIC; fig|243277.26.peg.2789; -.
DR eggNOG; COG4097; Bacteria.
DR HOGENOM; CLU_003827_19_0_6; -.
DR Proteomes; UP000000584; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd06198; FNR_like_3; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR47354:SF8; 1,2-PHENYLACETYL-COA EPOXIDASE, SUBUNIT E; 1.
DR PANTHER; PTHR47354; NADH OXIDOREDUCTASE HCR; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR PRINTS; PR00410; PHEHYDRXLASE.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000584};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..326
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 450 AA; 51143 MW; F0314C75F4229954 CRC64;
MIKWNWVMSR VKYTLWVVVG IVTLLWVQAE PTLFGSTNLF QWRSGLVQFS GILALMLMSL
AMLLALRLPL IEQWTQGIDK GYRIHKWLGI SALLLGIFHW LAYHLPKWLI SLELLTKPAR
LNGSGPNSNL SGLALWLKEA KPLAMEIGEW GFYALIVLLV VSLWSAIKYK PFRLTHRLMA
VVYLLIALHS VILLKKAYWG EPIYWLTMLF IVVGSWAACY SLLGLVGRQS RYPAHVKAFH
YCPNSQTLDL TIQLDKPWLG HKAGQFAYLK FAGEEPHPFT IACAHQGSQL RFLIKELGDF
TTGLHQRLQN GKSLEVEGPY GKFDFSTQQP QIWIGGGVGI APFMAGLDWL MRERAHPPVH
LFFCCHQIDP DLCAELRHKA QLAGVSLTII DSSVDPHLSA DDIARRCGDL SRFEIYFCGP
IAFSNSLKKA LKPYQVDLSR QFHEEQFVMR
//
