ID Q9KTV6_VIBCH Unreviewed; 308 AA.
AC Q9KTV6;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:AAF93946.1};
GN OrderedLocusNames=VC_0781 {ECO:0000313|EMBL:AAF93946.1};
OS Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF93946.1, ECO:0000313|Proteomes:UP000000584};
RN [1] {ECO:0000313|EMBL:AAF93946.1, ECO:0000313|Proteomes:UP000000584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39315 / El Tor Inaba N16961
RC {ECO:0000313|Proteomes:UP000000584};
RX PubMed=10952301; DOI=10.1038/35020000;
RA Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA Nelson K.E., Read T.D., Tettelin H., Richardson D., Ermolaeva M.D.,
RA Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.,
RA Utterback T., Fleishmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT cholerae.";
RL Nature 406:477-483(2000).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AE003852; AAF93946.1; -; Genomic_DNA.
DR PIR; F82281; F82281.
DR RefSeq; NP_230430.1; NC_002505.1.
DR AlphaFoldDB; Q9KTV6; -.
DR STRING; 243277.VC_0781; -.
DR DNASU; 2615324; -.
DR EnsemblBacteria; AAF93946; AAF93946; VC_0781.
DR KEGG; vch:VC_0781; -.
DR PATRIC; fig|243277.26.peg.745; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_39_5_6; -.
DR Proteomes; UP000000584; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd08466; PBP2_LeuO; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30118:SF6; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO; 1.
DR PANTHER; PTHR30118; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000584}.
FT DOMAIN 7..64
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 308 AA; 34503 MW; 2EDE8F3419765FF3 CRC64;
MIMLRDYDLN LLTVFDSVMK LGSVSKAADK LGMTSAAVSQ NLSRLREQVG DPLFIRQGRG
LQPTQYALNM HKHVAEGLSA IRFGLETDAG FDPATSKREF IIGGQGYFDL VVLPPLLQKI
SDIAPHITVN LKSYEDDHFT PSQVLSEREA DLFLAALPIS HPSIVTTQVA EEALVVVYAK
NHPRLGSTLS FEQFFAEKHT ALTSRRFGNY LFSSLVDQVL PARRVHYQSE SMLNLMATAS
VTDLLCFTPK RLADMWAEKL GLQIQPLPFE IRSVPTFMCW HKAKQQDKGL IWLREQIEAI
LCANPQSI
//
