ID Q9L231_STRCO Unreviewed; 300 AA.
AC Q9L231;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CAB71248.1};
GN OrderedLocusNames=SCO6801 {ECO:0000313|EMBL:CAB71248.1};
GN ORFNames=SC1A2.10 {ECO:0000313|EMBL:CAB71248.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB71248.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB71248.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AL939129; CAB71248.1; -; Genomic_DNA.
DR RefSeq; NP_630873.1; NC_003888.3.
DR RefSeq; WP_003972197.1; NZ_VNID01000002.1.
DR AlphaFoldDB; Q9L231; -.
DR STRING; 100226.gene:17764459; -.
DR PaxDb; 100226-SCO6801; -.
DR PATRIC; fig|100226.15.peg.6911; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_11; -.
DR InParanoid; Q9L231; -.
DR OrthoDB; 4131546at2; -.
DR PhylomeDB; Q9L231; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0032993; C:protein-DNA complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd08423; PBP2_LTTR_like_6; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 300 AA; 31319 MW; 2C52866BE3B5F14C CRC64;
MIEARRLHIL RAVADHRTVT AAAAALYLTP SAVSQQLAAL EQETGHRLVE RGAKGVRLTP
AGEILLSHTN AVLAQLERAE AELAAYGSGE AGTVTVASFA TGIALVVAPA LARLAESAPG
IRVRVQDAEG DASLPMVLDR QVDVAVAVEY RGAPPADDPR LTHVSLYAEP FDAVVPVAHR
LADADEVPLA ELAKDTWIGP YPGNPCHDVV VLACESAGFQ PRLEHSSDDF RAVVSLAAAD
AGVALVPRSA LLGTDLTGVV VRPVDGVAPT RRVFAAVRRG AEDHPLIRPV LDALGDAARA
//
