ID Q9LN87_ARATH Unreviewed; 549 AA.
AC Q9LN87;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 24-JAN-2024, entry version 98.
DE SubName: Full=T12C24.11 {ECO:0000313|EMBL:AAF88098.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAF88098.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|EMBL:AAF88098.1}
RP NUCLEOTIDE SEQUENCE.
RA Chao Q., Brooks S., Buehler E., Johnson-Hopson C., Khan S., Kim C.,
RA Shinn P., Altafi H., Bei Q., Chin C., Chiou J., Choi E., Conn L.,
RA Conway A., Gonzales A., Hansen N., Howng B., Koo T., Lam B., Lee J.,
RA Lenz C., Li J., Liu A., Liu K., Liu S., Mukharsky N., Nguyen M., Palm C.,
RA Pham P., Sakano H., Schwartz J., Southwick A., Thaveri A., Toriumi M.,
RA Vaysberg M., Yu G., Federspiel N.A., Theologis A., Ecker J.R.;
RT "Genomic sequence for Arabidopsis thaliana BAC T12C24 from chromosome I.";
RL Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAF88098.1}
RP NUCLEOTIDE SEQUENCE.
RA Cheuk R., Shinn P., Brooks S., Buehler E., Chao Q., Johnson-Hopson C.,
RA Khan S., Kim C., Altafi H., Bei B., Chin C., Chiou J., Choi E., Conn L.,
RA Conway A., Gonzalez A., Hansen N., Howing B., Koo T., Lam B., Lee J.,
RA Lenz C., Li J., Liu A., Liu J., Liu S., Mukharsky N., Nguyen M., Palm C.,
RA Pham P., Sakano H., Schwartz J., Southwick A., Thaveri A., Toriumi M.,
RA Vaysberg M., Yu G., Davis R., Federspiel N., Theologis A., Ecker J.;
RL Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AAF88098.1}
RP NUCLEOTIDE SEQUENCE.
RA Shinn P., Brooks S., Buehler E., Chao Q., Johnson-Hopson C., Khan S.,
RA Kim C., Altafi H., Bei B., Chin C., Chiou J., Choi E., Conn L., Conway A.,
RA Gonzalez A., Hansen N., Howing B., Koo T., Lam B., Lee J., Lenz C., Li J.,
RA Liu A., Liu J., Liu S., Mukharsky N., Nguyen M., Palm C., Pham P.,
RA Sakano H., Schwartz J., Southwick A., Thaveri A., Toriumi M., Vaysberg M.,
RA Yu G., Davis R., Federspiel N., Theologis A., Ecker J.;
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; AC025417; AAF88098.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9LN87; -.
DR ExpressionAtlas; Q9LN87; baseline and differential.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR45968:SF3; OS04G0573100 PROTEIN; 1.
DR PANTHER; PTHR45968; OSJNBA0019K04.7 PROTEIN; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR000137-3};
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 255..269
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 97
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 210
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 486..487
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 526..527
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT DISULFID 419..478
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-3"
SQ SEQUENCE 549 AA; 59233 MW; BB3030379BFD7909 CRC64;
MEIVSPNYSF MRDATGSPTT SYYDYIIIGG GTAGCPLAAT LSQNASVLLL ERGDSPYNNP
NITRLSAFGA ALSDLSESSP SQRFVSEDGV INARARVLGG GSALNAGFYT RAGTKYVRNM
GWDGALANES YQWVEAKVAF QPPMGRWQTA VRDGLLEAGI VPNNGFTYDH INGTKFGGTI
FDRNGNRHTA ADLLEYADPK GITVLLHATV HRILFRTRGT TKPIANGVVY RDRTGQAHRA
YLKEGALSEI ILSAGTLGSP QLLMLSGVGP SAQLQAQNIT VVMDQPHVGQ GMYDNPMNAV
FVPSPVPVEV SLIEVVGITG EGTYVEAAGG ENFGGGGGGS SGSSSTRDYY AMFSPRATLL
ESNSMTKLSS AQPFQGGFLL EKVMGPLSTG HLELKTRNPK DNPIVTFNYF QHPDDLKRCV
RGIQTIERVV QSKAFSRYKY ADVSFEYLLN LTASTPVNLR PPRSGPGASL PPSAEEFCQH
TVTTIWHYHG GCVVGRVVDG DYKVIGIDRL RVIDMSTVGY CPGTNPQATV MMLGRYMGVK
ILRERLTKK
//
