ID Q9M3X0_HORVU Unreviewed; 405 AA.
AC Q9M3X0;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Putative kinetochore protein {ECO:0000313|EMBL:CAB85492.1};
GN Name=cbf5 {ECO:0000313|EMBL:CAB85492.1};
OS Hordeum vulgare (Barley).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=4513 {ECO:0000313|EMBL:CAB85492.1};
RN [1] {ECO:0000313|EMBL:CAB85492.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Developing caryopsis {ECO:0000313|EMBL:CAB85492.1};
RX PubMed=11151678; DOI=10.1007/s004120000109;
RA ten Hoopen R., Manteuffel R., Dolezel J., Malysheva L., Schubert I.;
RT "Evolutionary conservation of kinetochore protein sequences in plants.";
RL Chromosoma 109:482-489(2000).
CC -!- SIMILARITY: Belongs to the pseudouridine synthase TruB family.
CC {ECO:0000256|ARBA:ARBA00008999}.
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DR EMBL; AJ277097; CAB85492.1; -; mRNA.
DR AlphaFoldDB; Q9M3X0; -.
DR EnsemblPlants; HORVU.MOREX.r2.2HG0099960.1; HORVU.MOREX.r2.2HG0099960.1.CDS.1; HORVU.MOREX.r2.2HG0099960.
DR EnsemblPlants; HORVU.MOREX.r2.2HG0099980.1.mrna1; HORVU.MOREX.r2.2HG0099980.1.mrna1.cds1; HORVU.MOREX.r2.2HG0099980.1.
DR Gramene; HORVU.MOREX.r2.2HG0099960.1; HORVU.MOREX.r2.2HG0099960.1.CDS.1; HORVU.MOREX.r2.2HG0099960.
DR Gramene; HORVU.MOREX.r2.2HG0099980.1.mrna1; HORVU.MOREX.r2.2HG0099980.1.mrna1.cds1; HORVU.MOREX.r2.2HG0099980.1.
DR ExpressionAtlas; Q9M3X0; baseline and differential.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd02572; PseudoU_synth_hDyskerin; 1.
DR CDD; cd21148; PUA_Cbf5; 1.
DR Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR012960; Dyskerin-like.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR002501; PsdUridine_synth_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR004802; tRNA_PsdUridine_synth_B_fam.
DR InterPro; IPR032819; TruB_C.
DR InterPro; IPR004521; Uncharacterised_CHP00451.
DR NCBIfam; TIGR00425; CBF5; 1.
DR NCBIfam; TIGR00451; unchar_dom_2; 1.
DR PANTHER; PTHR23127; CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5; 1.
DR PANTHER; PTHR23127:SF0; H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1; 1.
DR Pfam; PF08068; DKCLD; 1.
DR Pfam; PF01472; PUA; 1.
DR Pfam; PF16198; TruB_C_2; 1.
DR Pfam; PF01509; TruB_N; 1.
DR SMART; SM01136; DKCLD; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 61..119
FT /note="Dyskerin-like"
FT /evidence="ECO:0000259|SMART:SM01136"
FT DOMAIN 310..384
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 44712 MW; C71A2FCC14FD4E60 CRC64;
MSSTPPAVAS PASEHTKSKK KKSKSKDASS DPAADTTSLA DAEAKTDGYM IKPQALVPSL
DTSTWPLLLK NYDRLNVRTG HYTPLPSGHS PLKRPLAEYL RYGVINLDKP SNPSSHEVVA
WIKRLLRVEK TGHSGTLDPK VTGNLIVCVD RATRLVKSQQ GAGKEYVCIA RFHAAVPDTA
RVARALESLT GAVFQRPPLI SAVKRQLRVR TIYESKLLEH DAERHLAVFW ISCEAGTYVR
TLCVHLGLLL GVGAHMQELR RVRSGILGEQ DNMVTMHDVM DAMWALDNHK DESYIRRVVM
PLEVILTSYK RLVVKDSAVN AICYGAKLMI PGLLRFENDI DVGEEVVLMT TKGEAIAIGI
AEMPTAVMAT CDHGAVAKIK RVVMDRDTYP RKWGLGPVAL KLWIH
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