ID Q9MX27_ONCMY Unreviewed; 219 AA.
AC Q9MX27;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=MHC class II alpha {ECO:0000313|EMBL:CAB96450.1};
DE Flags: Fragment;
GN Name=onmy-DAA {ECO:0000313|EMBL:CAB96450.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:CAB96450.1};
RN [1] {ECO:0000313|EMBL:CAB96450.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10906388; DOI=10.1016/S0145-305X(00)00034-3;
RA Grimholt U., Getahun A., Hermsen T., Stet R.J.;
RT "The major histocompatibility class II alpha chain in salmonid fishes.";
RL Dev. Comp. Immunol. 24:751-763(2000).
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DR EMBL; AJ251431; CAB96450.1; -; mRNA.
DR AlphaFoldDB; Q9MX27; -.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR001003; MHC_II_a_N.
DR PANTHER; PTHR19944:SF86; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00993; MHC_II_alpha; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00920; MHC_II_alpha; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 2: Evidence at transcript level;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW MHC II {ECO:0000256|ARBA:ARBA00023182}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..219
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004330172"
FT DOMAIN 98..192
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 219
FT /evidence="ECO:0000313|EMBL:CAB96450.1"
SQ SEQUENCE 219 AA; 24208 MW; EA676F3B07D0CA48 CRC64;
MKTSMIVLIL CCQVYAEDKV LHTDIYINGC SDSDGVDMYG LDGEELWYAD FNKKEGVVAL
PPFADQISFP GYYEQAVGNQ RTCKGDLGVD IKAYKNPPET IDPPHSSIYP RDDVELGVEN
TLICHVSGFF PSPVRVRWTR NDQNVTEGGR ISTPYPNTDV TFNQFSSLSF TPEEGDIYGC
TVEHKALTEP LTRIWEPEVS QPSVGPAVFC GVGLTLGLL
//
