ID Q9NB28_BRAFL Unreviewed; 245 AA.
AC Q9NB28;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=HMG box transcription factor AmphiSox1/2/3 {ECO:0000313|EMBL:AAF81765.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739 {ECO:0000313|EMBL:AAF81765.1};
RN [1] {ECO:0000313|EMBL:AAF81765.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10993671; DOI=10.1006/dbio.2000.9810;
RA Holland L.Z., Schubert M., Holland N.D., Neuman T.;
RT "Evolutionary conservation of the presumptive neural plate markers
RT AmphiSox1/2/3 and AmphiNeurogenin in the invertebrate chordate amphioxus.";
RL Dev. Biol. 226:18-33(2000).
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DR EMBL; AF271787; AAF81765.1; -; mRNA.
DR AlphaFoldDB; Q9NB28; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd22028; HMG-box_SoxA_SoxB_SoxG; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR022097; SOX_fam.
DR PANTHER; PTHR10270:SF161; SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED; 1.
DR PANTHER; PTHR10270; SOX TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF12336; SOXp; 1.
DR PRINTS; PR00886; HIGHMOBLTY12.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267}.
FT DOMAIN 22..90
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 22..90
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 28158 MW; F4B58A2F4C162299 CRC64;
MSTNMMMHQE RKEDEAAKKD HVKRPMNAFM VWSRIQRRKI AEDNPKMHNS EISRRLGEMW
KELSAEEKKP FVEESKRLRA EHMEKYPDYK YRPRRKLKTM MKNSSFPTMP GGMPPNYFPA
SNCSPPPALQ MSMPEQYGHM NGYMSGYHSS MMRDPGNPYS HQVIPSSAAA TTAGSMPTRY
DMAALTYSTY ASMPPTTSYT TSSCALQPYP VSSYPSTDFC APVKPERTLP ASYDDHIRPY
YSEHC
//
