ID Q9NZP3_HUMAN Unreviewed; 162 AA.
AC Q9NZP3;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Olfactory receptor {ECO:0000313|EMBL:AAF40350.1};
DE Flags: Fragment;
GN Name=HSA12 {ECO:0000313|EMBL:AAF40350.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAF40350.1};
RN [1] {ECO:0000313|EMBL:AAF40350.1}
RP NUCLEOTIDE SEQUENCE.
RA Giorgi D.G., Rouquier S.P.;
RL Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAF40350.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10706615; DOI=10.1073/pnas.040580197;
RA Rouquier S., Blancher A., Giorgi D.;
RT "The olfactory receptor gene repertoire in primates and mouse: evidence for
RT reduction of the functional fraction in primates.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:2870-2874(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AF179761; AAF40350.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9NZP3; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR48001; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR48001:SF130; OLFACTORY RECEPTOR 1E1-RELATED; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:AAF40350.1};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..162
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAF40350.1"
FT NON_TER 162
FT /evidence="ECO:0000313|EMBL:AAF40350.1"
SQ SEQUENCE 162 AA; 17680 MW; 99A5BA75D0603A34 CRC64;
VAICFPLHYT AIMSPMLCLA LVALSWVLTT FHAMLHTLLM ARLCFCADNV IPHFFCDMSA
LLKLAFSDTR VNEWVIFIMG GLILVIPFLL ILGSYARIVS SILKVPSSKG ICKALSTCGS
HLSVVSLFYG TVIGLYLCSS ANSSTLKDTV MAMMYTVVTP ML
//
