ID Q9P929_NEUCS Unreviewed; 270 AA.
AC Q9P929;
DT 01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=Homocitrate synthase {ECO:0000313|EMBL:AAF66618.1};
DE EC=2.3.3.14 {ECO:0000313|EMBL:AAF66618.1};
DE Flags: Fragment;
OS Neurospora crassa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=5141 {ECO:0000313|EMBL:AAF66618.1};
RN [1] {ECO:0000313|EMBL:AAF66618.1}
RP NUCLEOTIDE SEQUENCE.
RA Schmidhauser T.J., Chen D., Wan Y.;
RT "Identification of a cosmid clone containing the Neurospora lys-5 and un-4
RT genes, isolation of a partial lys-5 cDNA and associated chromosome
RT walking.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AF142777; AAF66618.1; -; mRNA.
DR AlphaFoldDB; Q9P929; -.
DR VEuPathDB; FungiDB:NCU05526; -.
DR GO; GO:0004410; F:homocitrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044283; P:small molecule biosynthetic process; IEA:UniProt.
DR Gene3D; 1.10.238.260; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR002034; AIPM/Hcit_synth_CS.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR10277:SF48; HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED; 1.
DR PANTHER; PTHR10277; HOMOCITRATE SYNTHASE-RELATED; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00816; AIPM_HOMOCIT_SYNTH_2; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase {ECO:0000313|EMBL:AAF66618.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AAF66618.1}.
FT DOMAIN 1..138
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAF66618.1"
SQ SEQUENCE 270 AA; 29548 MW; DA4C78F4FDC5A23F CRC64;
VIEYVKSKGL EVRFSSEDSF RSDLVDLLSL YRAVDKVGVH RVGIADTVGC ASPRQVYDLV
RTLRGVVSCD IETHFHDDTG CAIANAYCAL EAGATHIDTS VLGIGERNGI TPLGGLMARM
IVTSPDYVKS KYKLHKLKEL EDLVAEAVEI NTPFNNPITG FCAFTHKAGI HAKAILNNPS
TYEILNPADF GLTRYVHFAS RLTGWNAVKT RVGQLGLEMT DDQVKECTAK IKALADVRPI
AIDDADSIIR TFHLGLHEQN KVQPPAVVEN
//
