ID Q9RCY5_STRCO Unreviewed; 294 AA.
AC Q9RCY5;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 125.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CAB63174.1};
GN OrderedLocusNames=SCO0925 {ECO:0000313|EMBL:CAB63174.1};
GN ORFNames=SCM10.13 {ECO:0000313|EMBL:CAB63174.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB63174.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB63174.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AL939107; CAB63174.1; -; Genomic_DNA.
DR RefSeq; NP_625223.1; NC_003888.3.
DR RefSeq; WP_003977934.1; NZ_VNID01000004.1.
DR AlphaFoldDB; Q9RCY5; -.
DR STRING; 100226.gene:17758508; -.
DR PaxDb; 100226-SCO0925; -.
DR PATRIC; fig|100226.15.peg.919; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_4_11; -.
DR InParanoid; Q9RCY5; -.
DR OrthoDB; 3181812at2; -.
DR PhylomeDB; Q9RCY5; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0032993; C:protein-DNA complex; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd05466; PBP2_LTTR_substrate; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 294 AA; 32096 MW; ABBC89BB5936C148 CRC64;
MQLQQLQYFV AVAETRHFTR AAEVVHVAQP SLSQQIKALE RELGADLFLR ARGNITLTDA
GEALLPLARR ILADADTARH EVLELAQLRR GRVRLGATPS LCTGLLPDVL RAFHDRYPGI
QLLIEEGGSH DLVRELARGA LDLALVVLPL PTASPALTTV ELLREDLVVV SSPESPRPGG
GRRAVRITDL EGERLVMFRH GYDLRELTVA ACRSAGFEPD FAVEGGEMDA VLGFVRAGLG
MAVVPRMVAA RSGRGLRVTP LARPGLYRTI ALAHRSDVAP PRAARELQRM LLER
//
