ID   Q9TTT6_RABIT            Unreviewed;        82 AA.
AC   Q9TTT6;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   24-JAN-2024, entry version 74.
DE   SubName: Full=Inducible nitric oxide synthase NOS2 {ECO:0000313|EMBL:AAF09500.1};
DE   Flags: Fragment;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986 {ECO:0000313|EMBL:AAF09500.1};
RN   [1] {ECO:0000313|EMBL:AAF09500.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=New Zealand White {ECO:0000313|EMBL:AAF09500.1};
RC   TISSUE=Kidney {ECO:0000313|EMBL:AAF09500.1};
RA   Tsao L.S., O'Brien W.J.;
RL   Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAG24286.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=New Zealand White {ECO:0000313|EMBL:AAG24286.1};
RC   TISSUE=Heart myocardium {ECO:0000313|EMBL:AAG24286.1};
RX   PubMed=11053770; DOI=10.1016/S0891-5849(00)00364-6;
RA   Shi Y., Pritchard K.A., Baker J.E.;
RT   "Chronic myocardial hypoxia increases nitric oxide synthase and decreases
RT   caveolin-3.";
RL   Free Radic. Biol. Med. 29:695-703(2000).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; AF198443; AAF09500.1; -; mRNA.
DR   EMBL; AF200351; AAG24286.1; -; mRNA.
DR   AlphaFoldDB; Q9TTT6; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR   PANTHER; PTHR19384:SF56; NITRIC OXIDE SYNTHASE, INDUCIBLE; 1.
DR   PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00175; NAD_binding_1; 1.
DR   PRINTS; PR00371; FPNCR.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
PE   2: Evidence at transcript level;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630}.
FT   DOMAIN          25..81
FT                   /note="Oxidoreductase FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF00175"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAF09500.1"
FT   NON_TER         82
FT                   /evidence="ECO:0000313|EMBL:AAF09500.1"
SQ   SEQUENCE   82 AA;  9396 MW;  73244479A4B965F6 CRC64;
     DPVPCFVRSA SGFQLPEDPS HPCILIGPGT GIAPFRSFWQ QRLHDSEYKG LRGGRMILVF
     GCRHPDEDHL YWEELQEMVR KG
//