ID Q9TV41_ATEBE Unreviewed; 407 AA.
AC Q9TV41;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=von Willebrand factor {ECO:0000256|ARBA:ARBA00016619};
DE Flags: Fragment;
OS Ateles belzebuth (White-bellied spider monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Atelidae;
OC Atelinae; Ateles.
OX NCBI_TaxID=9507 {ECO:0000313|EMBL:AAD50539.1};
RN [1] {ECO:0000313|EMBL:AAD50539.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9667998; DOI=10.1006/mpev.1998.0517;
RA Stanhope M.J., Madsen O.J., Waddell V.G., Cleven G.C., de Jong W.W.,
RA Springer M.S.;
RT "Highly congruent molecular support for a diverse superordinal clade of
RT endemic African mammals.";
RL Mol. Phylogenet. Evol. 9:501-508(1998).
CC -!- SUBUNIT: Multimeric. Interacts with F8.
CC {ECO:0000256|ARBA:ARBA00025858}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR EMBL; AF061059; AAD50539.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9TV41; -.
DR GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR CDD; cd01450; vWFA_subfamily_ECM; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR032361; VWA_N2.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF70; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00092; VWA; 2.
DR Pfam; PF16164; VWA_N2; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 39..215
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 260..407
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAD50539.1"
FT NON_TER 407
FT /evidence="ECO:0000313|EMBL:AAD50539.1"
SQ SEQUENCE 407 AA; 45411 MW; E2F981D37D9B253E CRC64;
EPGGLVIPPT DAPVSPTTPY VEDVSEAPLH DFYCSKLLDL VFLLDGSSRL SEAEFEVLKA
FVVDMMERLR ISQKWVRVAV VEYHDGSHAY IGLKDRKRPS ELRRIASQVK YAGSQVASTS
EVLKYTLFQI FGKIDRPEAS RIILLLMASQ EPQRMSRNFV RYVQGLKKKK VIVIPVGIGP
HANLKQIRLI EKQAPENKAF VLSGVDELEQ QRDEIVSYLC DLAPEASSPT MPPHMAQVTV
GPGLLGVSPL GHKRKSVVLD VAFVLEGSDK IGEADFNRTK EFMEEVIQRM DVGQDSIHVT
VLQYSYMVTV EYPFSEAQSK GDILQRVREI RYQGGNRTNT GLALQHLSEH SFLVSQGDRE
QAPNLVYMVT GNPASDEIKR LPGDIQVVPI GVGPHANVQE LERIGWP
//
