ID Q9UL73_HUMAN Unreviewed; 119 AA.
AC Q9UL73;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Myosin-reactive immunoglobulin heavy chain variable region {ECO:0000313|EMBL:AAD56277.1};
DE Flags: Fragment;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAD56277.1};
RN [1] {ECO:0000313|EMBL:AAD56277.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9614934; DOI=10.1006/clin.1998.4531;
RA Wu X., Liu B., Van der Merwe P.L., Kalis N.N., Berney S.M., Young D.C.;
RT "Myosin-reactive autoantibodies in rheumatic carditis and normal fetus.";
RL Clin. Immunol. Immunopathol. 87:184-192(1998).
CC -!- SUBUNIT: Immunoglobulins are composed of two identical heavy chains and
CC two identical light chains; disulfide-linked.
CC {ECO:0000256|ARBA:ARBA00038737}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Membrane {ECO:0000256|ARBA:ARBA00004370}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; AF035041; AAD56277.1; -; mRNA.
DR PIR; PH0876; PH0876.
DR PIR; S12416; S12416.
DR AlphaFoldDB; Q9UL73; -.
DR PeptideAtlas; Q9UL73; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0019814; C:immunoglobulin complex; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR CDD; cd04981; IgV_H; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23266; IMMUNOGLOBULIN HEAVY CHAIN; 1.
DR PANTHER; PTHR23266:SF323; IMMUNOGLOBULIN HEAVY VARIABLE 4-30-2-RELATED; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Immunoglobulin {ECO:0000256|ARBA:ARBA00043265};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 1..95
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAD56277.1"
FT NON_TER 119
FT /evidence="ECO:0000313|EMBL:AAD56277.1"
SQ SEQUENCE 119 AA; 13219 MW; 1BDB86B6420EA0BE CRC64;
QVQLQESGPG LVKPSETLSL TCTVSGGSIC SYYWSWIRQP PGKGLEWIGY IYYSGSTNYT
PSLKSRVTIS VDRSKNQFSL KLTSLTAADT AVYFCARLSN WGPYYFDYWG QGTLVTVSS
//
