ID Q9V229_PYRAB Unreviewed; 632 AA.
AC Q9V229;
DT 01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 129.
DE SubName: Full=3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase), containing one PUA domain and 2 4Fe-4S binding domains {ECO:0000313|EMBL:CAB49169.1};
DE SubName: Full=Phosphoadenosine phosphosulfate reductase family protein {ECO:0000313|EMBL:CCE69621.1};
GN OrderedLocusNames=PAB0168 {ECO:0000313|EMBL:CAB49169.1};
OS Pyrococcus abyssi (strain GE5 / Orsay).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=272844 {ECO:0000313|EMBL:CAB49169.1, ECO:0000313|Proteomes:UP000000810};
RN [1] {ECO:0000313|EMBL:CAB49169.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Orsay {ECO:0000313|EMBL:CAB49169.1};
RA Genoscope;
RL Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CAB49169.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Orsay {ECO:0000313|EMBL:CAB49169.1};
RX PubMed=10736225; DOI=10.1006/jmbi.2000.3593;
RA Gaspin C., Cavaille J., Erauso G.;
RT "Archaeal homologs of eukaryotic methylation guide small nucleolar RNAs:
RT lessons from the Pyrococcus genomes.";
RL J. Mol. Biol. 297:895-906(2000).
RN [3] {ECO:0000313|EMBL:CAB49169.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Orsay {ECO:0000313|EMBL:CAB49169.1};
RX PubMed=11381026; DOI=10.1101/gr.GR1653R;
RA Lecompte O., Ripp R., Puzos-Barbe V., Duprat S., Heilig R., Dietrich J.,
RA Thierry J.C., Poch O.;
RT "Genome evolution at the genus level: comparison of three complete genomes
RT of hyperthermophilic archaea.";
RL Genome Res. 11:981-993(2001).
RN [4] {ECO:0000313|EMBL:CAB49169.1, ECO:0000313|Proteomes:UP000000810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GE5 / Orsay {ECO:0000313|Proteomes:UP000000810}, and Orsay
RC {ECO:0000313|EMBL:CAB49169.1};
RX PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA Cohen G., Barbe V., Flament D., Galperin M., Heilig R., Ripp R.,
RA Lecompte O., Prieur D., Poch O., Quellerou J., Thierry J.C.,
RA Van der Oost J., Weissenbach J., Zivanovic Y., Forterre P.;
RT "An integrated analysis of the genome of the hyperthermophilic archaeon
RT Pyrococcus abyssi.";
RL Mol. Microbiol. 47:1495-1512(2003).
RN [5] {ECO:0000313|EMBL:CCE69621.1, ECO:0000313|Proteomes:UP000009139}
RP GENOME REANNOTATION.
RC STRAIN=GE5 {ECO:0000313|EMBL:CCE69621.1}, and GE5 / Orsay
RC {ECO:0000313|Proteomes:UP000009139};
RX PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA Gao J., Wang J.;
RT "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT Pyrococcus furiosus DSM 3638.";
RL Curr. Microbiol. 64:118-129(2012).
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DR EMBL; AJ248283; CAB49169.1; -; Genomic_DNA.
DR EMBL; HE613800; CCE69621.1; -; Genomic_DNA.
DR PIR; B75215; B75215.
DR RefSeq; WP_010867369.1; NC_000868.1.
DR AlphaFoldDB; Q9V229; -.
DR STRING; 272844.PAB0168; -.
DR GeneID; 1495134; -.
DR KEGG; pab:PAB0168; -.
DR PATRIC; fig|272844.11.peg.262; -.
DR eggNOG; arCOG00073; Archaea.
DR HOGENOM; CLU_026622_0_0_2; -.
DR OrthoDB; 5817at2157; -.
DR Proteomes; UP000000810; Chromosome.
DR Proteomes; UP000009139; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd01713; PAPS_reductase; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR002500; PAPS_reduct.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004521; Uncharacterised_CHP00451.
DR NCBIfam; TIGR00451; unchar_dom_2; 1.
DR PANTHER; PTHR43196; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR PANTHER; PTHR43196:SF1; SULFATE ADENYLYLTRANSFERASE SUBUNIT 2; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF01507; PAPS_reduct; 1.
DR Pfam; PF01472; PUA; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS50890; PUA; 1.
PE 4: Predicted;
FT DOMAIN 569..599
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 601..630
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 632 AA; 72672 MW; 18A85174A67F6E14 CRC64;
MRKKGPVVLG RFWIYWCEKC NVPLISEKCS VHGEDGVFKI TLTPPGDVRF AFERDIELIR
AVFLEHYGVD IKELMDGKIV LLNKIPGEDD SYEIIFDGFI FGIISFDPRS LKWRPGLKEE
GARLLWEKFG KRMKKWVIID RGAVEPVKNG ANVLPVGIIE AEESIRRNDE VIVVSEDGEV
VGVGIAKKDY EELINPSSRG TGIKMKRKAK GSGRRTNGKK AKIEDVIRAN SQALEEKVKE
AKEFMRKTAE KFKLPVSVAF SGGKDSLAVL GLALEEFDEF TVFFNNTGIE FPETVEYVES
LRKELEPKGV RFIVADAGDA FWRAVNIFSP PGMDYRWCCK VTKLGPITLA IKRHFPQGVL
MFVGQRKFES FKRYKQGRVW RNSWVPNEIG AAPIFHWTAL EVWLYIFSRK LRYNPLYERG
IDRIGCFLCP SQSLAEIERL KKEKPELWSK WEKELEKWRK KLNLPKEWIE YGFWRWRKLG
KREVALAKDL GVEIPRERKW DVIEFSIEEE GESFIVRPST RINLRRIREV APILGEVEEG
SNYLKAGKNL FDAEKNIIVS PSHEEAIASM FLLKRAYECV GCGVCVTSCP ENAIFIDEKR
KKAVVIAERC THCRECMNSC PLVVIQGIDR IL
//
