ID Q9X4D2_ACTNA Unreviewed; 533 AA.
AC Q9X4D2;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=Type-1 fimbrial major subunit {ECO:0000313|EMBL:AAD28827.1};
GN Name=fimP {ECO:0000313|EMBL:AAD28827.1};
OS Actinomyces naeslundii.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1655 {ECO:0000313|EMBL:AAD28827.1};
RN [1] {ECO:0000313|EMBL:AAD28827.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=B-1-K {ECO:0000313|EMBL:AAD28827.1};
RX PubMed=10225854;
RA Li T., Johansson I., Hay D.I., Stromberg N.;
RT "Strains of Actinomyces naeslundii and Actinomyces viscosus exhibit
RT structurally variant fimbrial subunit proteins and bind to different
RT peptide motifs in salivary proteins.";
RL Infect. Immun. 67:2053-2059(1999).
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DR EMBL; AF106035; AAD28827.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9X4D2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 2.60.40.740; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR026466; Fim_isopep_form_D2_dom.
DR InterPro; IPR048052; FM1-like.
DR InterPro; IPR032364; GramPos_pilinD1_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR006311; TAT_signal.
DR NCBIfam; NF033902; iso_D2_wall_anc; 1.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR04226; RrgB_K2N_iso_D2; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF16555; GramPos_pilinD1; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..533
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039329545"
FT TRANSMEM 504..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 496..533
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
SQ SEQUENCE 533 AA; 56817 MW; D65207B99B24528E CRC64;
MHSLNTRRGL GLAAAMTLAA GALVAPTGAA APADPNGSTI DPDAATTLTV HKCEQTDTNG
VKEGTGNEDP QAECKPVSDV EFTITKLNVD LTTYDGWKTL ADLKGDVVKA GALKSTTVQK
ITTGANGLAS FTDAQTEVGA YLVSETRTPD KVIPAEDFVV TLPMTNPQDT AKWNYNVHVY
PKNTLSGVDK QVTDKPAPGS GRDITYTITT SIPKVDYPGG ARIKRYEVVD RLDKRIKKEA
LTPVVKIVGQ NEVTLADTTD YTLITAEGKD HNWATIQLTE EGRRKASEAR YNGNGETKLQ
VTLTAKFDAA VNLEGDLSNT AGLIPNDSPN FTWDPNNPGT TTDIPGIPTT PVLSKYGKVV
LTKTGTDQLA DKTKYNGAQF QVYECTKTAS GATVRDSDPS TQTVDPVTIG GEKTFTTAGQ
GTVEINYLRA NDYVNGAKKD QLTDEDYYCL VETKAPEGYS LQADPLPFRV LAEKAEKKAA
TEVTVTDIPK NAGFRLPLTG ANGVIFLTVA GALLVAGGAV VAYANKRRHV AKH
//
