ID Q9X5B6_CLOSY Unreviewed; 267 AA.
AC Q9X5B6;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=2-hydroxyglutaryl-CoA dehydratase {ECO:0000313|EMBL:AAD31675.1, ECO:0000313|EMBL:RGY58790.1};
DE SubName: Full=2-hydroxyglutaryl-CoA dehydratase activator protein {ECO:0000313|EMBL:CUO17898.1};
GN Name=hgdC {ECO:0000313|EMBL:AAD31675.1};
GN Synonyms=hgdC_2 {ECO:0000313|EMBL:CUO17898.1};
GN ORFNames=DXA34_11535 {ECO:0000313|EMBL:RGY58790.1}, ERS852479_00964
GN {ECO:0000313|EMBL:CUO17898.1};
OS Clostridium symbiosum (Bacteroides symbiosus).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1512 {ECO:0000313|EMBL:AAD31675.1};
RN [1] {ECO:0000313|EMBL:AAD31675.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=10491198; DOI=10.1046/j.1432-1327.1999.00748.x;
RA Hans M., Sievers J., Muller U., Bill E., Vorholt J.A., Linder D.,
RA Buckel W.;
RT "2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum.";
RL Eur. J. Biochem. 265:404-414(1999).
RN [2] {ECO:0000313|EMBL:CUO17898.1, ECO:0000313|Proteomes:UP000095573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2789STDY5834864 {ECO:0000313|EMBL:CUO17898.1,
RC ECO:0000313|Proteomes:UP000095573};
RG Pathogen Informatics;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RGY58790.1, ECO:0000313|Proteomes:UP000286557}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OF01-1AC {ECO:0000313|EMBL:RGY58790.1,
RC ECO:0000313|Proteomes:UP000286557};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; AF123384; AAD31675.1; -; Genomic_DNA.
DR EMBL; CYZY01000010; CUO17898.1; -; Genomic_DNA.
DR EMBL; QSDB01000028; RGY58790.1; -; Genomic_DNA.
DR RefSeq; WP_003501725.1; NZ_SPFP01000002.1.
DR AlphaFoldDB; Q9X5B6; -.
DR eggNOG; COG1924; Bacteria.
DR BRENDA; 5.6.1.9; 772.
DR Proteomes; UP000095573; Unassembled WGS sequence.
DR Proteomes; UP000286557; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR NCBIfam; TIGR00241; CoA_E_activ; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR PANTHER; PTHR32329:SF2; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 7..256
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
SQ SEQUENCE 267 AA; 28055 MW; 6F589C6186062323 CRC64;
MSGIYTLGID VGSTASKCIV LKDGKEIVAK SLIDVGAGTS GPQRAIEAVL NEAGMKKEDM
AYTLATGYGR TSLMDGIADK QMSELSCHAK GATFLFPNVH TVIDIGGQDV KVLHIDNGAM
TNFQMNDKCA AGTGRFLDVM ARVLEVKVED LGRLGAMSRK KVGISSTCTV FAESEVISQL
AMGTDKCDII DGIHRSVAHR VTGLAHRIGV VPDVVMTGGV AQNEGVVKAL QDELGCPINT
SPLTQYNGAL GAALLAWQAA SRRQSNS
//
