ID Q9X8M3_STRCO Unreviewed; 531 AA.
AC Q9X8M3;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 133.
DE SubName: Full=Exporter {ECO:0000313|EMBL:CAB40866.1};
GN OrderedLocusNames=SCO3366 {ECO:0000313|EMBL:CAB40866.1};
GN ORFNames=SCE94.17c {ECO:0000313|EMBL:CAB40866.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAB40866.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAB40866.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AL939116; CAB40866.1; -; Genomic_DNA.
DR PIR; T36377; T36377.
DR RefSeq; NP_627574.1; NC_003888.3.
DR RefSeq; WP_011028938.1; NZ_VNID01000023.1.
DR AlphaFoldDB; Q9X8M3; -.
DR STRING; 100226.gene:17760988; -.
DR PaxDb; 100226-SCO3366; -.
DR PATRIC; fig|100226.15.peg.3429; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_000960_22_3_11; -.
DR InParanoid; Q9X8M3; -.
DR OrthoDB; 7375466at2; -.
DR PhylomeDB; Q9X8M3; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd17502; MFS_Azr1_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR004638; EmrB-like.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00711; efflux_EmrB; 1.
DR PANTHER; PTHR23501:SF197; COMD; 1.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01036; TCRTETB.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 23..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..504
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 507..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 55216 MW; E7A1C8F42D63BD13 CRC64;
MAEKTEAATG GAGAGKQPRS VRVVLLALMI AMMLAMLDNM IIGTAMPTIV GELGGLEHLS
WVVTAYTLAT AASTPLWGKL GDMYGRKGVF MTSIVIFLAG SALSGMAQDM GQLIGFRAVQ
GLGAGGLMVG VMAIIGDLIP PRERGKYQGM IAGVMALSMI GGPLVGGTIT DHWGWRWSFY
INIPLGVIAL IAISAVLHLP KKRSEARIDY LGAALLTIGI TAIVLVTTWG GTEYAWTSAR
IMELIGIGVA ALVGFVFWQT RAAEPILPLH IFRSRNFTLM SVIGFIVGFV MFGATLFLPL
YQQSVQGASA TNSGLLLLPM LGAMLVTSMV AGRVTTSTGR YKIFPVAGGA LMTVGLYLLS
TMDTDTTRFT SGLYMAVVGL GMGCLMQITM LVAQNSVEMK DMGVASSSTT LFRTLGSSFG
VAIMGALFNN RVQDVMAERA AGSGAKATEQ SATLTADALN ALPAAIRDAY QHAVSAGTHT
AFLLGSAVAV LALVASFFVK EVPLKGAGPK AADAPADGDP ATAKAPVTEA V
//
