ID Q9XVS2_CAEEL Unreviewed; 454 AA.
AC Q9XVS2;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 159.
DE SubName: Full=RRM domain-containing protein {ECO:0000313|EMBL:CAB02757.1};
GN Name=sup-46 {ECO:0000313|EMBL:CAB02757.1,
GN ECO:0000313|WormBase:C25A1.4};
GN ORFNames=C25A1.4 {ECO:0000313|WormBase:C25A1.4}, CELE_C25A1.4
GN {ECO:0000313|EMBL:CAB02757.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB02757.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB02757.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB02757.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- INTERACTION:
CC Q9XVS2; P91277: hrpk-1; NbExp=3; IntAct=EBI-311961, EBI-320476;
CC Q9XVS2; Q9GRY9: nova-1; NbExp=4; IntAct=EBI-311961, EBI-320508;
CC Q9XVS2; D0VWM8: tdp-1; NbExp=2; IntAct=EBI-311961, EBI-311955;
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DR EMBL; BX284601; CAB02757.1; -; Genomic_DNA.
DR PIR; T19433; T19433.
DR RefSeq; NP_492677.1; NM_060276.3.
DR AlphaFoldDB; Q9XVS2; -.
DR SMR; Q9XVS2; -.
DR DIP; DIP-24275N; -.
DR IntAct; Q9XVS2; 13.
DR STRING; 6239.C25A1.4.2; -.
DR EPD; Q9XVS2; -.
DR PaxDb; 6239-C25A1-4-1; -.
DR PeptideAtlas; Q9XVS2; -.
DR EnsemblMetazoa; C25A1.4.1; C25A1.4.1; WBGene00045383.
DR GeneID; 172881; -.
DR KEGG; cel:CELE_C25A1.4; -.
DR UCSC; C25A1.4.1; c. elegans.
DR AGR; WB:WBGene00045383; -.
DR WormBase; C25A1.4; CE08369; WBGene00045383; sup-46.
DR eggNOG; KOG4212; Eukaryota.
DR GeneTree; ENSGT00940000168568; -.
DR HOGENOM; CLU_019566_2_0_1; -.
DR InParanoid; Q9XVS2; -.
DR OMA; VHGMFPG; -.
DR OrthoDB; 317787at2759; -.
DR PhylomeDB; Q9XVS2; -.
DR PRO; PR:Q9XVS2; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00045383; Expressed in embryo and 4 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR CDD; cd12386; RRM2_hnRNPM_like; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23003; RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q9XVS2,
KW ECO:0007829|PeptideAtlas:Q9XVS2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 45..123
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 188..265
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 385..454
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 49345 MW; 66A26676E57A29E9 CRC64;
MNRNRRDGPQ RDVKRERRSR SRSPRRSRIG AAVGSNNGNS SSNNRMVFIT NIAYEARWVD
LKSLVREKGG EVAFCELLED RNGKPKGNAV VEFETREGAE KCVENLQKFD WKGRTIIAKE
IRDPNAFFRT IKTETGIDYL SRTGGGGAGG RGPPPKDLDR PTRTGTYDLF GLNMEFLRQH
NIEPPLCERI FIANLAFNVG TDKLYEVFGM AGKITWMDFR IDKEGKSKGV CVIQYTHPIE
AVQAVSMLNG QRLFDRNLVV KMDRFDKELE HKEGGLPRGL ESIGMGLGAE GAPLSNVHGM
FPGDASVPFT APAAPFVGGP QVVSAGGFGG VVEQANFARS VMNNGPFGGN AGVGGAGGAT
FAQPDVFGVN GAGGLAGAAT PQATRVIIIR NLPSDYTWQI VRDRVRNFGE VDSVDMMAPG
AARIRFATFQ DAERARAALY GSTVEGRMIS VDYA
//
