ID Q9XWM0_CAEEL Unreviewed; 283 AA.
AC Q9XWM0;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 145.
DE SubName: Full=RING-type domain-containing protein {ECO:0000313|EMBL:CAA21635.1};
GN ORFNames=CELE_Y38F1A.2 {ECO:0000313|EMBL:CAA21635.1}, Y38F1A.2
GN {ECO:0000313|EMBL:CAA21635.1, ECO:0000313|WormBase:Y38F1A.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA21635.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAA21635.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA21635.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX284602; CAA21635.1; -; Genomic_DNA.
DR PIR; T26682; T26682.
DR RefSeq; NP_496760.1; NM_064359.3.
DR AlphaFoldDB; Q9XWM0; -.
DR IntAct; Q9XWM0; 1.
DR STRING; 6239.Y38F1A.2.1; -.
DR PaxDb; 6239-Y38F1A-2; -.
DR EnsemblMetazoa; Y38F1A.2.1; Y38F1A.2.1; WBGene00012606.
DR GeneID; 174939; -.
DR KEGG; cel:CELE_Y38F1A.2; -.
DR UCSC; Y38F1A.2; c. elegans.
DR AGR; WB:WBGene00012606; -.
DR WormBase; Y38F1A.2; CE21607; WBGene00012606; -.
DR eggNOG; KOG2164; Eukaryota.
DR GeneTree; ENSGT00390000017123; -.
DR HOGENOM; CLU_072335_1_0_1; -.
DR InParanoid; Q9XWM0; -.
DR OMA; LITPVKC; -.
DR OrthoDB; 154493at2759; -.
DR PhylomeDB; Q9XWM0; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9XWM0; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00012606; Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16553; RING-HC_RNF170; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038896; RNF170.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR22894:SF5; E3 UBIQUITIN-PROTEIN LIGASE RNF170; 1.
DR PANTHER; PTHR22894; UNCHARACTERIZED; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 105..149
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 283 AA; 32711 MW; 974CE071FDB1A80C CRC64;
MEQGVPATSS EIPPFTENIT IPEVVSETVT EPDEDWLWPS DPDVELATQI TMAIAVIFIV
KAIFDAWQSR RRQRAASRMD ENAERNQIIT QRRISEALHQ SSHECPICLA NASFPVLTDC
GHIFCCECII QYWQQSKAIV TPCDCAMCRS TFYMLLPVHW PTMGTSEETD DHIQENNIRI
DDYNRRFSIN RPVLDYIRDI PILIPYLIRN FFNNDIFTLV YQVRIGFVFI CVITYFLLPS
DMVPESIYGI IGFLDDCIIG ILVFGAMFRW LREYMADRGL ARN
//
