ID Q9Y1M7_PETMA Unreviewed; 63 AA.
AC Q9Y1M7;
DT 01-NOV-1999, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1999, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Homeobox protein SIX12 {ECO:0000313|EMBL:AAD39901.1};
DE Flags: Fragment;
GN Name=Six12 {ECO:0000313|EMBL:AAD39901.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|EMBL:AAD39901.1};
RN [1] {ECO:0000313|EMBL:AAD39901.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain and spinal cord {ECO:0000313|EMBL:AAD39901.1};
RX PubMed=10381573; DOI=10.1016/S0925-4773(99)00045-3;
RA Seo H.C., Curtiss J., Mlodzik M., Fjose A.;
RT "Six class homeobox genes in Drosophila belong to three distinct families
RT and are involved in head development.";
RL Mech. Dev. 83:127-139(1999).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR EMBL; AF108816; AAD39901.1; -; mRNA.
DR AlphaFoldDB; Q9Y1M7; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR PANTHER; PTHR10390:SF33; PROTEIN OPTIX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682}.
FT DOMAIN 9..63
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT REGION 37..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAD39901.1"
FT NON_TER 63
FT /evidence="ECO:0000313|EMBL:AAD39901.1"
SQ SEQUENCE 63 AA; 7644 MW; 8D1D55194ECC294D CRC64;
KFPLPRTIWD GEQKTHCFKE RTRNLLREWY LQDPYPNPSK KRELAQATGL TPTQVGNWFK
NRR
//
