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Database: UniProt
Entry: Q9YGZ8
LinkDB: Q9YGZ8
Original site: Q9YGZ8 
ID   OPSD_CHELB              Reviewed;         353 AA.
AC   Q9YGZ8;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   16-APR-2014, entry version 64.
DE   RecName: Full=Rhodopsin;
GN   Name=rho;
OS   Chelon labrosus (Thicklip grey mullet) (Mugil chelo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;
OC   Acanthomorpha; Acanthopterygii; Percomorpha; Mugilomorpha; Mugilidae;
OC   Chelon.
OX   NCBI_TaxID=48171;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Retina;
RA   Archer S.N., Hirano J.;
RT   "Comparative analysis of opsins in Mediterranian coastal fish.";
RL   Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Visual pigments such as rhodopsin and porphyropsin are
CC       light-absorbing molecules that mediate vision. Rhodopsin consists
CC       of an apoprotein, opsin, covalently linked to 11-cis-retinal. This
CC       receptor is coupled to the activation of phospholipase C.
CC       Porphyropsin consists of opsin covalently linked to 11-cis 3,4-
CC       didehydroretinal.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Rod shaped photoreceptor cells which mediates
CC       vision in dim light.
CC   -!- PTM: Phosphorylated on some or all of the serine and threonine
CC       residues present in the C-terminal region.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       Opsin subfamily.
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DR   EMBL; Y18669; CAA77251.1; -; mRNA.
DR   ProteinModelPortal; Q9YGZ8; -.
DR   SMR; Q9YGZ8; 1-348.
DR   HOVERGEN; HBG107442; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1070.10; -; 1.
DR   Gene3D; 4.10.840.10; -; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR001760; Opsin.
DR   InterPro; IPR027430; Retinal_BS.
DR   InterPro; IPR000732; Rhodopsin.
DR   InterPro; IPR019477; Rhodopsin_N.
DR   Pfam; PF00001; 7tm_1; 1.
DR   Pfam; PF10413; Rhodopsin_N; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00238; OPSIN.
DR   PRINTS; PR00579; RHODOPSIN.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   PROSITE; PS00238; OPSIN; 1.
PE   2: Evidence at transcript level;
KW   Chromophore; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Lipoprotein; Membrane; Palmitate; Phosphoprotein;
KW   Photoreceptor protein; Receptor; Retinal protein;
KW   Sensory transduction; Transducer; Transmembrane; Transmembrane helix;
KW   Vision.
FT   CHAIN         1    353       Rhodopsin.
FT                                /FTId=PRO_0000197659.
FT   TOPO_DOM      1     36       Extracellular.
FT   TRANSMEM     37     61       Helical; Name=1; (Potential).
FT   TOPO_DOM     62     73       Cytoplasmic.
FT   TRANSMEM     74     98       Helical; Name=2; (Potential).
FT   TOPO_DOM     99    113       Extracellular.
FT   TRANSMEM    114    133       Helical; Name=3; (Potential).
FT   TOPO_DOM    134    152       Cytoplasmic.
FT   TRANSMEM    153    176       Helical; Name=4; (Potential).
FT   TOPO_DOM    177    202       Extracellular.
FT   TRANSMEM    203    230       Helical; Name=5; (Potential).
FT   TOPO_DOM    231    252       Cytoplasmic.
FT   TRANSMEM    253    276       Helical; Name=6; (Potential).
FT   TOPO_DOM    277    284       Extracellular.
FT   TRANSMEM    285    309       Helical; Name=7; (Potential).
FT   TOPO_DOM    310    353       Cytoplasmic.
FT   MOD_RES     296    296       N6-(retinylidene)lysine (By similarity).
FT   LIPID       322    322       S-palmitoyl cysteine (By similarity).
FT   CARBOHYD      2      2       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD     15     15       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    200    200       N-linked (GlcNAc...) (Potential).
FT   DISULFID    110    187       By similarity.
SQ   SEQUENCE   353 AA;  39505 MW;  8C4B6F4847B3C632 CRC64;
     MNGTEGPYFY IPMVNTTGIV RSPYEYPQYY LVNPAAYAAL GAYMFLLILV GFPVNFLTLY
     VTLEHKKLRT PLNYILLNLA VADLFMVLGG FTTTMYTSMH GYFVLGRLGC NVEGFFATLG
     GEIALWSLVV LAIERWVVVC KPISNFRFSE DHAIMGLAFT WVMASACAVP PLVGWSRYIP
     EGMQCSCGID YYTRAEGFNN ESFVIYMFVC HFLIPLVVVF FCYGRLLCAV KEAAAAQQES
     ETTQRAEREV SRMVVIMVVA FLVCWCPYAG VAWYIFTHQG SEFGPLFMTF PAFFAKSSSI
     YNPMIYICMN KQFRHCMITT LCCGKNPFEE EEGASTTSKT EASSVSSSSV SPA
//
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