ID Q9YHF0_LITPI Unreviewed; 313 AA.
AC Q9YHF0;
DT 01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1999, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Agrin B19 isoform {ECO:0000313|EMBL:AAC68700.1};
DE Flags: Fragment;
OS Lithobates pipiens (Northern leopard frog) (Rana pipiens).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Lithobates.
OX NCBI_TaxID=8404 {ECO:0000313|EMBL:AAC68700.1};
RN [1] {ECO:0000313|EMBL:AAC68700.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:AAC68700.1};
RA Werle M.J., Jones M.A., Stanco A.M.;
RT "Agrin produced by Schwann cells does not induce the aggregation of AChRs
RT at the frog neuromuscular junction.";
RL Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AF096690; AAC68700.1; -; mRNA.
DR AlphaFoldDB; Q9YHF0; -.
DR GO; GO:0005604; C:basement membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF83; AGRIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00054; Laminin_G_1; 2.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}.
FT DOMAIN 1..142
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 138..176
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 187..313
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DISULFID 166..175
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAC68700.1"
FT NON_TER 313
FT /evidence="ECO:0000313|EMBL:AAC68700.1"
SQ SEQUENCE 313 AA; 34372 MW; B31292D1439548F4 CRC64;
GQKTDAKGDF VSLALHDGHL EYRYDLGKGA AVIRNKEKIP LNTWVSVTLE RNGRKGQMRI
NNKEQVTGES PKSRKTPHNA LNLKESLYVG GAPDFSKLAR SAAISTSFEG SIQKLNIKGF
PVLREENILN AIEIATFLGH PCTQKPYPCQ NGGLCIPKKE SYDCVCQRGF SGGQCEKATI
EKSAGSSEAV SFDGKTYLEY HKVTKNQLTN EIPDHAAAEN PDDPSEKALL TNEFELSIKT
EATQGLILWS GKGTERSDYI ALAVVGGYVQ MMYDLGSKPV ILRSTVPVNT NQWIRIKALR
NNRDGILQVG NEA
//
