ID Q9Z0I9_MOUSE Unreviewed; 1703 AA.
AC Q9Z0I9;
DT 01-MAY-1999, integrated into UniProtKB/TrEMBL.
DT 01-MAY-1999, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Collagen alpha3(VI) {ECO:0000313|EMBL:AAD01978.1};
DE Flags: Fragment;
GN Name=Col6a3 {ECO:0000313|EMBL:AAD01978.1, ECO:0000313|MGI:MGI:88461};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAD01978.1};
RN [1] {ECO:0000313|EMBL:AAD01978.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F1 {ECO:0000313|EMBL:AAD01978.1};
RX PubMed=12009329; DOI=10.1016/S0945-053X(02)00009-4;
RA Dziadek M., Kazenwadel J.S., Hendrey J.A., Pan T.C., Zhang R.Z., Chu M.L.;
RT "Alternative splicing of transcripts for the alpha 3 chain of mouse
RT collagen VI: identification of an abundant isoform lacking domains N7-N10
RT in mouse and human.";
RL Matrix Biol. 21:227-241(2002).
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DR EMBL; AF034136; AAD01978.1; -; mRNA.
DR RefSeq; NP_001229937.1; NM_001243008.1.
DR PeptideAtlas; Q9Z0I9; -.
DR GeneID; 12835; -.
DR KEGG; mmu:12835; -.
DR AGR; MGI:88461; -.
DR CTD; 1293; -.
DR MGI; MGI:88461; Col6a3.
DR OrthoDB; 5359724at2759; -.
DR BioGRID-ORCS; 12835; 6 hits in 79 CRISPR screens.
DR ChiTaRS; Col6a3; mouse.
DR Genevisible; Q9Z0I9; MM.
DR GO; GO:0005581; C:collagen trimer; IDA:MGI.
DR GO; GO:0062023; C:collagen-containing extracellular matrix; IBA:GO_Central.
DR GO; GO:0031012; C:extracellular matrix; IDA:MGI.
DR GO; GO:0005615; C:extracellular space; IDA:MGI.
DR GO; GO:0042383; C:sarcolemma; IDA:MGI.
DR GO; GO:0051402; P:neuron apoptotic process; IDA:MGI.
DR GO; GO:0043491; P:phosphatidylinositol 3-kinase/protein kinase B signal transduction; IDA:MGI.
DR GO; GO:0009411; P:response to UV; IDA:MGI.
DR CDD; cd01481; vWA_collagen_alpha3-VI-like; 1.
DR CDD; cd01450; vWFA_subfamily_ECM; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 9.
DR InterPro; IPR041900; vWA_collagen_alpha3-VI-like.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF70; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00092; VWA; 9.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00327; VWA; 8.
DR SUPFAM; SSF53300; vWA-like; 9.
DR PROSITE; PS50234; VWFA; 9.
PE 2: Evidence at transcript level;
KW Collagen {ECO:0000313|EMBL:AAD01978.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1703
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004338806"
FT DOMAIN 38..212
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 241..414
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 444..619
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 638..811
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 836..1008
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1026..1202
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1230..1405
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1433..1606
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1636..1703
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1610..1630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1703
FT /evidence="ECO:0000313|EMBL:AAD01978.1"
SQ SEQUENCE 1703 AA; 185783 MW; 38A14AD16EE75526 CRC64;
MRKHRHLPLV AVFSLLFSGI AMTRAQQHGD VKNGAAADIV FLVDSSWSAG KDRFLLVQEF
LSDVVESLAV GDNDFHFALV RLNGNPHTEF LLNTYHSKQE VLSHIANMSY IGGSNQTGKG
LEYVIHSHLT EASGSRAADG VPQVIVVLTD GQSEDGFALP SAELKSADVN VFAVGVEGAD
ERALGEVASE PLSMHVFNLE NVTSLHGLVG NLVSCIHSSV NPERAGDKES LKDITAQDSA
DIIFLIDGSQ NTGNANFDVI RDFLVNVLER LSVGNQQVQV GVVQYSEEPI TMFSLNSYPS
KAAVLDAVKG LSLVGGESAN IGQALDFVVE NHFTRAGGSR VEEGVPQVLV LISAGPSSDE
IRDSVVALKQ ASVFSFGLGA QAASRAELQH IATDDSLVFT VPEFRSFGDL QEQILPYLVG
VAQRHIVLQP PAIVTQVMEV NKRDIVFLVD GSSSLGPSNF NAIRDFVTRV IQRLEIGQDL
VQVSVAQYAD TVKPEFYLNS YTNKRDAVTA VRKMRALNGS ALYTGSSLDF VRNNLFTSSA
GHRAAEGVPK LLVLITGGKS LDEVSQPAQE LKRGSIMALA VGSKAADEDE LKEIAFDSSL
VFIPAEFRPA PLQNMLPSLM APLRTLTGTT EVHVNKRDII FLLDGSDNVG KNNFPYVRDF
VTNLVNSLDV GSDNIRVGLV QFSDTPVTEF SLDTYQTKSE LLAHLRRLQL KGGSGLNAGS
ALSYIHANHF TEAGGSRTRE HVPQLLLLLM AGPSEDAYLQ AANALVRSGV LTFCVGTNRA
DKAELEHIAF NPSLVYLMDD FRSLPSLPQQ LIQPLTTYVS GGVQEVPLSQ PESKRDILFL
FDGSVNVLGQ FPAVRDFLYR IIEELDVKPD GTRVAIAQFS DDVRLESRFS EHQTKAEILN
LVKKMKLKTG KALNLGYALD YALRNIFVRS AGSRIEDNVQ QFLVLLVAGR SSDAVAGPAS
SLKQRGVVPF IFQAKNANPS ELEQIVLSPA FILAAESLPK IGDLQSQIVS LLKAEQGSGP
VSGEKDVVFL IDGSEGVRSG FPLLKDFVQR VVESLDVGPD RVRVALVQYS DRTRPEFYLN
SHMDQQGVIS AIRRLTLLGG PTPNTGAALE FVLRNILTSS TGSRIAEGVP QLLIVLTAEP
SGDDVRGPSV VLKQGGAVPI GIGIGNADIS EMQTISFIPD FAVAIPTFRE LGTIQQVISE
RVIQLNREEL SSLKPILTPS TGAGVGSKKD VVFLIDGSRN AGPEFQYIRT LIERIVEYLD
IGFDTTRVAV IQFSEDSKME FPLNAHFSKD EVQNAVRRLR PKGGSQVYIG NALEYVLKNI
FQRPLGSRIE EGVPQFLVLI SSGKSDDEVD DSAVELKQFG VAPLTIARHT DQEELVKISL
SPEYVYSVST FRELPRLEQK LLKPITTLTS QQIHQILAST RYPPSVVESD AADIVFLIDS
SDAVKPDGIA HIRDFVSRIV RRLNIGPSKV RIGVVQFSND VFPEFYLKTH KSQSSVLEAI
RRLRFKGGSP LNTGRALEFV ARNLFVKSAG SRIEDGVPQH LVLFLGGKSQ DDVARHAQVI
SSSGIVSLGI GDRNIDRTDL QTITNDPRLV FTVREFRELP NIEERVMLSF GPSGATPQPP
GVDLPSPSRP EKKKADIVFL LDGSINFRRD SFQEVLRFAS EIVDTVYEDG DSIRVGLVQY
NSDPTDEFFL RDFSTKRQII DAI
//
