ID MNMG_CHLPN Reviewed; 611 AA.
AC Q9Z7T7; Q9JQ82;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 01-MAY-2013, entry version 87.
DE RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG;
DE AltName: Full=Glucose-inhibited division protein A;
GN Name=mnmG; Synonyms=gidA;
GN OrderedLocusNames=CPn_0617, CP_0130, CpB0643;
OS Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=83558;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CWL029;
RX PubMed=10192388; DOI=10.1038/7716;
RA Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL Nat. Genet. 21:385-389(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR39;
RX PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F.,
RA White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J.,
RA Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C.,
RA Dodson R.J., Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F.,
RA McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.;
RT "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia
RT pneumoniae AR39.";
RL Nucleic Acids Res. 28:1397-1406(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J138;
RX PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT "Comparison of whole genome sequences of Chlamydia pneumoniae J138
RT from Japan and CWL029 from USA.";
RL Nucleic Acids Res. 28:2311-2314(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW-183;
RA Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT other Chlamydia strains based on whole genome sequence analysis.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: NAD-binding protein involved in the addition of a
CC carboxymethylaminomethyl (cmnm) group at the wobble position (U34)
CC of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity).
CC -!- COFACTOR: FAD (By similarity).
CC -!- SUBUNIT: Homodimer (By similarity). Heterotetramer of two MnmE and
CC two MnmG subunits (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC -!- SIMILARITY: Belongs to the MnmG family.
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DR EMBL; AE001363; AAD18756.1; -; Genomic_DNA.
DR EMBL; AE002161; AAF38013.1; -; Genomic_DNA.
DR EMBL; BA000008; BAA98824.1; -; Genomic_DNA.
DR EMBL; AE009440; AAP98572.1; -; Genomic_DNA.
DR PIR; E72056; E72056.
DR PIR; F86567; F86567.
DR RefSeq; NP_224813.1; NC_000922.1.
DR RefSeq; NP_300673.1; NC_002491.1.
DR RefSeq; NP_444682.1; NC_002179.2.
DR RefSeq; NP_876915.1; NC_005043.1.
DR ProteinModelPortal; Q9Z7T7; -.
DR STRING; 115713.CPn0617; -.
DR PRIDE; Q9Z7T7; -.
DR EnsemblBacteria; AAD18756; AAD18756; CPn_0617.
DR EnsemblBacteria; AAF38013; AAF38013; CP_0130.
DR EnsemblBacteria; AAP98572; AAP98572; CpB0643.
DR EnsemblBacteria; BAA98824; BAA98824; BAA98824.
DR GeneID; 1467322; -.
DR GeneID; 895416; -.
DR GeneID; 919381; -.
DR GeneID; 962995; -.
DR KEGG; cpa:CP0130; -.
DR KEGG; cpj:CPj0617; -.
DR KEGG; cpn:CPn0617; -.
DR KEGG; cpt:CpB0643; -.
DR eggNOG; COG0445; -.
DR HOGENOM; HOG000201060; -.
DR KO; K03495; -.
DR OMA; AQMSCNP; -.
DR ProtClustDB; PRK05192; -.
DR BioCyc; CPNE115711:GI7B-130-MONOMER; -.
DR BioCyc; CPNE115713:GHEY-620-MONOMER; -.
DR BioCyc; CPNE138677:GH8N-608-MONOMER; -.
DR BioCyc; CPNE182082:GH4N-640-MONOMER; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:HAMAP.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR HAMAP; MF_00129; MnmG_GidA; 1; -.
DR InterPro; IPR004416; GidA.
DR InterPro; IPR026904; GidA-assoc_3.
DR InterPro; IPR002218; GIDA-rel.
DR InterPro; IPR020595; GIDA-rel_CS.
DR Pfam; PF01134; GIDA; 1.
DR Pfam; PF13932; GIDA_assoc_3; 1.
DR TIGRFAMs; TIGR00136; gidA; 1.
DR PROSITE; PS01280; GIDA_1; 1.
DR PROSITE; PS01281; GIDA_2; 1.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; FAD; Flavoprotein; NAD; tRNA processing.
FT CHAIN 1 611 tRNA uridine 5-carboxymethylaminomethyl
FT modification enzyme MnmG.
FT /FTId=PRO_0000117082.
FT NP_BIND 14 19 FAD (By similarity).
FT NP_BIND 274 288 NAD (Potential).
FT BINDING 126 126 FAD; via amide nitrogen and carbonyl
FT oxygen (By similarity).
FT BINDING 181 181 FAD (By similarity).
FT BINDING 371 371 FAD (By similarity).
SQ SEQUENCE 611 AA; 67565 MW; 5EAA284B9037A9E8 CRC64;
MWTHPIAYDV IVVGAGHAGC EAAYCSAKMG VSVLMLTSNL DTIAKLSCNP AVGGIGKGHI
VREIDALGGI MAEVTDQSGI QFRILNQTKG PAVRAPRAQV DKQLYHIHMK RLLENTPGLH
IMQATVESLL DKEGVISGVT TKEGWMFSGK TVVLSSGTFM RGLIHIGDRN FSGGRLGDPS
SQGLSEDLKK RGFPISRLKT GTPPRLLASS INFSCMEEQP GDLGVGFVHR TEPFQPPLPQ
LSCFITHTME KTKAIISANL HRSALYGGCI EGVGPRYCPS IEDKIVKFSD KERHHVFLEP
EGLHTQEIYA NGLSTSMPFD VQYDMIRSVL GLENAIITRP AYAIEYDYIH GNVIHPTLES
KLIEGLFLCG QINGTTGYEE AAAQGLIAGI NAVNKVFNRP PFIPSRQESY IGVMLDDLTT
QILDEPYRMF TGRAEHRLLL RQDNACARLS HYGYELGLLS EERYELVKKQ NQLLEEEKVR
LQKTFRQYGQ SVVSLAKALS RPEVSYDMLR EAFPNDIRDL GAVLNASLEM EIKYSGYIDR
QKILIQSLEK AESLLIPEDL DYKQITALSL EAQEKLAKFT PRTLGSASRI SGIASADIQV
LMIALKKHAH H
//
