ID R0E0C5_RALPI Unreviewed; 277 AA.
AC R0E0C5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Shikimate 5-dehydrogenase {ECO:0000313|EMBL:ENZ79098.1};
GN ORFNames=OR214_00668 {ECO:0000313|EMBL:ENZ79098.1};
OS Ralstonia pickettii OR214.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=1264675 {ECO:0000313|EMBL:ENZ79098.1, ECO:0000313|Proteomes:UP000013280};
RN [1] {ECO:0000313|EMBL:ENZ79098.1, ECO:0000313|Proteomes:UP000013280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OR214 {ECO:0000313|EMBL:ENZ79098.1,
RC ECO:0000313|Proteomes:UP000013280};
RX PubMed=23792748;
RA Utturkar S.M., Bollmann A., Brzoska R.M., Klingeman D.M., Epstein S.E.,
RA Palumbo A.V., Brown S.D.;
RT "Draft Genome Sequence for Ralstonia sp. Strain OR214, a Bacterium with
RT Potential for Bioremediation.";
RL Genome Announc. 1:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ79098.1}.
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DR EMBL; APMQ01000002; ENZ79098.1; -; Genomic_DNA.
DR RefSeq; WP_004627271.1; NZ_APMQ01000002.1.
DR AlphaFoldDB; R0E0C5; -.
DR PATRIC; fig|1264675.3.peg.664; -.
DR Proteomes; UP000013280; Unassembled WGS sequence.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd01065; NAD_bind_Shikimate_DH; 1.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR022893; Shikimate_DH_fam.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR PANTHER; PTHR21089; SHIKIMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21089:SF34; SHIKIMATE DEHYDROGENASE (NADP(+)); 1.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 12..94
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
FT DOMAIN 121..165
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
SQ SEQUENCE 277 AA; 29544 MW; D7D10A883F16C9FD CRC64;
MISGKTTLIA HIGYPTETFK SPMIYNPWFE QKGIDAVVMP MGVKAEDYPQ SFASICRFTN
LRGALITMPH KVTTVELVDE VTPAVRIAGA CNAVLKRDDG TLLGDQFDGA GFVRGVLRKG
RQLEGARVLL SGAGGVGSAI AASLAAAGVG ELALYDTRAE SAESLGRRLR EHYPALVVGT
GSNDPDGFDV VVNATPVGMK DDDPLPFDVA RIAPSCFVGE VVMKSEYTPL LRAARNKGCD
VQVGTDMLFE MIPAYLEFFG FGTATADELR RSAAIAY
//
