ID   R0EUM8_9BRAS            Unreviewed;       980 AA.
AC   R0EUM8;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=CARUB_v10025792mg {ECO:0000313|EMBL:EOA12832.1};
OS   Capsella rubella.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX   NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA12832.1, ECO:0000313|Proteomes:UP000029121};
RN   [1] {ECO:0000313|Proteomes:UP000029121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX   PubMed=23749190; DOI=10.1038/ng.2669;
RA   Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA   Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA   Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA   Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA   Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA   Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT   "The Capsella rubella genome and the genomic consequences of rapid mating
RT   system evolution.";
RL   Nat. Genet. 45:831-835(2013).
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DR   EMBL; KB870812; EOA12832.1; -; Genomic_DNA.
DR   RefSeq; XP_006279934.1; XM_006279872.1.
DR   AlphaFoldDB; R0EUM8; -.
DR   Proteomes; UP000029121; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR011713; Leu-rich_rpt_3.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR11017:SF565; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF07725; LRR_3; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT   DOMAIN          7..169
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   980 AA;  112354 MW;  022C5860C3AFFAA0 CRC64;
     MAASSGESWQ VFINFRGEEL RGNFISHLEG ALTLAEIKYY IDTKEVPSED LTVLFTRIEQ
     SEIALCIFSS KYAESKWCLD ELVKITEQVE KGKLRIIPVF FNVTPEEVKE QKGEFGLKLY
     GEGKRKRPNI SAWENALDSV PSKIGLNLKN FRNEREFVDK IVDSVKRVLE VIPLNGISKD
     LSSVSDSNGN ISSSHIEQPK ALPLDYGMEQ RLKQLEEKLD FDSLETQIVG IVGMPGIGKT
     ALAEMHFKKW NNRFVFKKII RVIREEINDE SDWLKDTLLN GKELNHKAQN FKRKIFVVLD
     DVSHKNQVKF LLKNLEWIKK GSKIVITTRD KSTIAELVHD IYIVPGLNDK DALELFKHHA
     FNDQDSSKTG NLLKLCKKYV DYAGGNPGAL KELGKELCGE DEAHWEARLA TLPHCCNPKI
     QSELRISYDK LSEQQKDAFL DIACFFRSEE EDYVKCLLDP YGPDSSEVVR DLAEKLLICI
     SAGRIEMHNL LCTFGQELGS SDENKSGKRM WNHEKIKNTL RSEQIILSQR IKKVRGIFLD
     TSKLEDGIPI DPDIFIERFN QQNLRYLKVY DSVCPKQCDV DCKVNLPDGL EFPFQEIRYL
     HWLKFPLDEL PPDFNPENLI DLRLPYSKIK RVWEAVKETP WLKWVDLSYS NKLTDLSALS
     KAFHLRRLNL EGCTVLDKLP EEMKNMKSLV FLNLRGCTML SSLPERLDLV SLKTLILSGC
     SKFINFELIS ENLEFLHLDG TAIQNLPWAI QNFQKLVLLN LKDCKMLKFL PECLDKLKAL
     EELILSGCGK LTSFPDTKEK MENLQILLLD GTKIKELPNI LLHSCNFKGQ VVLHRSPGMN
     GLSMLRRLCL SRNEEICSLH SSISQLYHLN WIDLKYCKNL LSIPTLPPNL QCLDAHACNS
     LKEVASPLAL LMPTQKIPCS FIFTNCEKLE QDAKKEIICY AHNKSRMISD ALNRHNKVFL
     YHPESSSTVQ IILIMFCFTL
//