ID   R0FDN6_9BRAS            Unreviewed;       847 AA.
AC   R0FDN6;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=DUF4378 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CARUB_v10000211mg {ECO:0000313|EMBL:EOA19961.1};
OS   Capsella rubella.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX   NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA19961.1, ECO:0000313|Proteomes:UP000029121};
RN   [1] {ECO:0000313|Proteomes:UP000029121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX   PubMed=23749190; DOI=10.1038/ng.2669;
RA   Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA   Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA   Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA   Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA   Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA   Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT   "The Capsella rubella genome and the genomic consequences of rapid mating
RT   system evolution.";
RL   Nat. Genet. 45:831-835(2013).
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DR   EMBL; KB870810; EOA19961.1; -; Genomic_DNA.
DR   RefSeq; XP_006287063.1; XM_006287001.1.
DR   AlphaFoldDB; R0FDN6; -.
DR   STRING; 81985.R0FDN6; -.
DR   GeneID; 17881243; -.
DR   KEGG; crb:17881243; -.
DR   eggNOG; KOG4727; Eukaryota.
DR   OrthoDB; 463864at2759; -.
DR   Proteomes; UP000029121; Unassembled WGS sequence.
DR   InterPro; IPR032795; DUF3741-assoc.
DR   InterPro; IPR025486; DUF4378.
DR   PANTHER; PTHR21726:SF69; DUF4378 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR21726; PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P DOWN SYNDROME CRITICAL REGION PROTEIN 5 -RELATED; 1.
DR   Pfam; PF14309; DUF4378; 1.
DR   Pfam; PF14383; VARLMGL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029121}.
FT   DOMAIN          78..104
FT                   /note="DUF3741"
FT                   /evidence="ECO:0000259|Pfam:PF14383"
FT   DOMAIN          667..814
FT                   /note="DUF4378"
FT                   /evidence="ECO:0000259|Pfam:PF14309"
FT   REGION          28..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          64..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          261..443
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..301
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        308..326
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..420
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   847 AA;  94078 MW;  AAF0D9A0A72B9AC6 CRC64;
     MEVVERKRSR GGFFNLIDWP GKSRKKLFSS SSSELSESKQ TKQTTQNLSK SRVSLIEVDE
     IGKSTSYNPR SDSSCCASSV TSDDGQGTRA PSVVARLMGL ESLPVPNVQE PRYNPDLDPF
     SLRTSRNTNR WDAYENLGYV NLRSDYDGIS WDHLDSRTNN GRNQPIERFQ SETFPPRSAK
     PICVTNNRHL SPIRSPGFVP SRNPIYVMEA ASRMIEPSPR IVARTRFSPS NSPSSVPMRI
     QDLRDKLEAA QKVSSRQISN DTFNLKNPSA KHNEKRTSTS LTTPSTSKFM GNSSSNGLKG
     KVKPSYVSAQ AKASTTPLSV TRNSGNQKEK AEAKKSIVRS QNGLRGAHIS MGKSMLKQNN
     QKQNCRDNQP SVTSFSNQKS SKVNTKVVNK GPVESGSISK QSGLTTASME KNTSLSLSRK
     KTLPRSKKLP NGMQKSGISD DKLTKRSENL IKCNITIDGG LSKGKDDRKK EMDVISFTFS
     SPIKGLSSDS LSSTQGIDQD TDSAVSFNVI GGDSLNVLLE QKLRELTSKL ESSSCSLTQE
     ESSCSFPKDE VDGMISQNGL DKVLPESESV SDCTSFYDKQ KFQIQAEEND VSSISTVTES
     DDLRSSCSKG FSDCGQAVEY GTVQSSSDQE FTWVSLNESH QVHDEFELSE SVITLTYSEA
     EERLDWELEY ISEILSSDQL MVKEFALGMA TDILPASLFD EMEGRGEATA AKINRKTLFD
     FVNNCLVLKC ERMFMGSCRG LLGKGGFLFE QRDWLAEELN REIHGLKKMR ELMMDELVDK
     EMSNFEGRWL DFERETYEEG IDIEAEIVST LVDDLVNDLV SGTQRRTLRQ RGGLVSALVE
     PDLLTVF
//