ID R0GR37_9BRAS Unreviewed; 346 AA.
AC R0GR37;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=fructokinase {ECO:0000256|ARBA:ARBA00038887};
DE EC=2.7.1.4 {ECO:0000256|ARBA:ARBA00038887};
GN ORFNames=CARUB_v10026709mg {ECO:0000313|EMBL:EOA13638.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA13638.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC towards starch formation. {ECO:0000256|ARBA:ARBA00037195}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00036647};
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004727}.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}.
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DR EMBL; KB870812; EOA13638.1; -; Genomic_DNA.
DR RefSeq; XP_006280740.1; XM_006280678.1.
DR AlphaFoldDB; R0GR37; -.
DR STRING; 81985.R0GR37; -.
DR GeneID; 17876236; -.
DR KEGG; crb:17876236; -.
DR eggNOG; KOG2855; Eukaryota.
DR OrthoDB; 5486729at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0008865; F:fructokinase activity; IEA:UniProt.
DR GO; GO:0006000; P:fructose metabolic process; IEA:UniProt.
DR CDD; cd01167; bac_FRK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43085:SF7; FRUCTOKINASE-7-RELATED; 1.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003704};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}.
FT DOMAIN 22..330
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 346 AA; 37285 MW; E75FB0D301C8DD70 CRC64;
MGENAISGNL KNLTIDTRDS ETLVVCFGEM LIDFVPTVGG VSLAEAPAFK KAPGGAPANV
AVGVSRLGGS SAFIGKVGDD EFGRMLADIL RLNNVDNSGM RFDHNARTAL AFVTLRADGE
REFLFFRHPS ADMLLSESEL DKNLIQKAKI FHYGSISLIE EPCRSTQLAA MKIAKASGSL
LSYDPNLRLP LWPSEDAARK EIMSIWNLAD VIKISEDEIT FLTGGDDPYD DNVVLQKLFH
PDLKLLVVSE GPNGCRYYTQ EFKGRVGGVK VKPVDTTGAG DAFVSGLLNS LASDLTLLKD
EKKLREALLF ANACGAITVT ERGAIPAMPS MDAVQDLLTS SASHRS
//
