ID R0HEQ4_9BRAS Unreviewed; 519 AA.
AC R0HEQ4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=CARUB_v10002864mg {ECO:0000313|EMBL:EOA22268.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA22268.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; KB870810; EOA22268.1; -; Genomic_DNA.
DR RefSeq; XP_006289370.1; XM_006289308.1.
DR AlphaFoldDB; R0HEQ4; -.
DR STRING; 81985.R0HEQ4; -.
DR GeneID; 17881994; -.
DR KEGG; crb:17881994; -.
DR eggNOG; KOG0166; Eukaryota.
DR OrthoDB; 1219011at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF89; IMPORTIN SUBUNIT ALPHA-9; 1.
DR Pfam; PF00514; Arm; 3.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT REPEAT 210..237
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 519 AA; 56513 MW; CAFCC0E08C004AD2 CRC64;
MADDGSASNR RDPIKSSVGN VAGQRRRQQA VTVAKERREL LVKAKRLCRV GTNGDVEDAC
VENEMLIDEE QPILEAQANK AVEELKSAVQ YQGKGAMQKR VTALRELRRL LSKSEFPPVK
AALSAGAIPL LVQCLSFGSP DEQLLESAWC LTNIAAGEPE ETKALLPALP LLIAHLGEKS
SAPVAEQCAW AIGNCAGEGE DLRNVLLSQG ALTPLARMLS PDKGSTVRTA AWALSNLIKG
PEPKAAAQLV RVDGILDAIL RHLKKTDEVT AKEIAWIIVY LSALSDIATS MLLKGGILQL
LLERLATSNS LQLLIPVLRS VGNFVAVDPK AILTIFIREQ NTEESIVGVL AKCLRSEHRV
LKKEAAWVLS NIAAGPIEHK RMIHSTEVMS LLLRLLSTSP FDIRKEIAYV LGNLCVESAE
GDTKPRIIQE HLVSIVSGGC LPGFIELVRS PDIEAARLGL QFIELVLRGM PNGEGPKLVE
GEDGIDAMER FQFHENEELR VMANSLVDKY FGEDYGIDE
//
