ID R0I305_9BRAS Unreviewed; 398 AA.
AC R0I305;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=tetraacyldisaccharide 4'-kinase {ECO:0000256|ARBA:ARBA00012071};
DE EC=2.7.1.130 {ECO:0000256|ARBA:ARBA00012071};
GN ORFNames=CARUB_v10013878mg {ECO:0000313|EMBL:EOA30738.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA30738.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- PATHWAY: Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A)
CC from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-
CC acetyl-alpha-D-glucosamine: step 6/6. {ECO:0000256|ARBA:ARBA00004870}.
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DR EMBL; KB870807; EOA30738.1; -; Genomic_DNA.
DR RefSeq; XP_006297840.1; XM_006297778.1.
DR AlphaFoldDB; R0I305; -.
DR STRING; 81985.R0I305; -.
DR GeneID; 17893901; -.
DR KEGG; crb:17893901; -.
DR eggNOG; ENOG502QRUA; Eukaryota.
DR OrthoDB; 469548at2759; -.
DR UniPathway; UPA00359; UER00482.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0009029; F:tetraacyldisaccharide 4'-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR HAMAP; MF_00409; LpxK; 1.
DR InterPro; IPR003758; LpxK.
DR PANTHER; PTHR42724; TETRAACYLDISACCHARIDE 4'-KINASE; 1.
DR PANTHER; PTHR42724:SF1; TETRAACYLDISACCHARIDE 4'-KINASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02606; LpxK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Lipid A biosynthesis {ECO:0000256|ARBA:ARBA00022556};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 398 AA; 44210 MW; 251BFD3DB56B8092 CRC64;
MEKLRKVVNE IAYTRDHSKS PALHRSLVPI LKLASSLYGV ALHIRRSLYR LSLLQKHRLP
VPVISVGNLS WGGNGKTPMV EYISQFLVDS GVSPLILTRG YAGGDEAKML ERHLRGGPAK
IGVGANRAST AAWFFKKYGC VDPSSIRTFF DQSFLHERAE AMTISKKIGA VILDDGMQHW
SLSRDLEIVM LNGIDPWGNG HLVPLGPLRE PLVALERADI VVVHHVDLIT KQSLRDIENT
IRGFKKSILI FYSNMVPKCL INVKNARSHV ALEALRCASV LCVSAIGSAE AFVKSIEMTG
ARCVDRLDFS DHHLFEARDV ETMRKRAKGL EQKSNSMPII VVTEKDYDRD PDILKCLDSY
TVLVLCSELQ ITPFIGTDGD SFKSTLTRVL AAKFCVSN
//
