ID R0K3E0_ANAPL Unreviewed; 429 AA.
AC R0K3E0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=SH2 domain-containing protein 4B {ECO:0000313|EMBL:EOB04197.1};
DE Flags: Fragment;
GN ORFNames=Anapl_00224 {ECO:0000313|EMBL:EOB04197.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB04197.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
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DR EMBL; KB742808; EOB04197.1; -; Genomic_DNA.
DR RefSeq; XP_012951500.1; XM_013096046.1.
DR AlphaFoldDB; R0K3E0; -.
DR OrthoDB; 5361172at2759; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR CDD; cd10351; SH2_SH2D4B; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035839; SH2D4B_SH2.
DR PANTHER; PTHR14388:SF7; SH2 DOMAIN-CONTAINING PROTEIN 4B; 1.
DR PANTHER; PTHR14388; T CELL-SPECIFIC ADAPTER PROTEIN TSAD; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 323..415
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 193..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 144..184
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 199..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 429
FT /evidence="ECO:0000313|EMBL:EOB04197.1"
SQ SEQUENCE 429 AA; 50749 MW; D08BD090B3255095 CRC64;
MLQQILRDMY IDPELLAELN EEQKQILFYK MREEQLRRWK EREEKARMEE AVLRRTARRK
QSDGKHVQWL CGKDGEVWVW VMGEAPGDKP YDQISEELIA ERARQQAQKE AEELWRQKEA
EITKKFRDAM AQEKARIVAE KWKIEIEDRK AAKLEEEKIQ EELKKREEEE RQKGEEQIRQ
QEEIRAKELY LSLKQAQQHS QHSDDDQEWE EQLRRSKAAD EERSHKARRA RDEYRRQSLR
AIQKGIVAGL SNLFQGTSLN NEQETKLNCN SASPLQSLSA ASSNIWERPS RPFSREVIIR
WFKEEQVPRR AGFERNTNRI AQWFHGIISR QEAEELLMNK SEGTFLVRVS EKIWGYALSY
RQQSGFKHFL VDASGDFYSF LGVDPNRHAT LTDLIDFHKE EIITSSGGEL LLEPCGQQKN
PPDYSPLFE
//
