ID R0K4G3_ANAPL Unreviewed; 984 AA.
AC R0K4G3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Sorting nexin-13 {ECO:0000313|EMBL:EOB04632.1};
DE Flags: Fragment;
GN ORFNames=Anapl_02803 {ECO:0000313|EMBL:EOB04632.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB04632.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KB742773; EOB04632.1; -; Genomic_DNA.
DR AlphaFoldDB; R0K4G3; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06873; PX_SNX13; 1.
DR CDD; cd08719; RGS_SNX13; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037437; SNX13_PX.
DR InterPro; IPR037896; SNX13_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..281
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 370..493
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 556..677
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOB04632.1"
FT NON_TER 984
FT /evidence="ECO:0000313|EMBL:EOB04632.1"
SQ SEQUENCE 984 AA; 114579 MW; 28A2DCE0D3B8E720 CRC64;
QTSLSIWGWG SLGVVLFLIT FGPFAIFYFA FYILCFVGGG FVVTLLFGKS NSEKYLEQCE
HSFLPCTSVG IPKCIEEMKR EARPIKIDRR LTGANIIDEP LQQVIQFSLR DYVQYWYYTL
SDDESFLLEI RQALQYALVQ FSARSKETDW QPYFTTRLVD DFGTHLRVFR KAQQRIAEKG
DQMKDQAEEL VDTFFEVEVE MEKEVCRDLV CTSPKDEEGF LRDLCEVLLY ILLPPGDFQN
KIMRYFVREI LSRGILLPLI NQLSDPDYIN QYVIWMIRDS NCNYEAFMNI IKLSDNIGEL
EAVKDKASEE LQYLRSLDTA GDDINTIKNQ INSLLYVIKV CDSRIQRLQS GKEIDTVKLA
ANFGKLCTVP LDHILVDNVA LQFFMDYMQQ TGGQAHLFFW MTVEGYRVTA QQQLEVLQSR
QKDGKHQTNQ TKGLLRAAAV GVYEQYLSEK ASPRVNIDDN LVAKLAETLN HEDPTPEIFD
DIQRKVYELM LRDERFYPSF KQNVLYVRML AELDMLKDPS FRGSDDGEGE SFNGSPTGSI
NLSLDDLSNV PSDETVQLHA YISDTGVCND HGKTYALYAI TVHRRNQNSE ETWKTYRRYS
DFHDFHMRIT EQFENLANIL KLPGKKTFNN MDREFLEKRK KDLNAYLQLL LNPEMMKASP
ALAHYVYDFL ENKAYSKGKG DFARKMDTFV NPLRNSMRNV SNAVKSLPDS LAEGMTKMSD
NMGKMSERLG QDIKQSFFKV PPLIQKTYSD PDHCRVAAPI DDNVDDNIPL RVMLLLMDEV
FDLKERNQWL RRNIKNLLQQ LIRATYGDTI NRYCFSFREL LSKLCCFDFR KIVDHVDWMT
SPEQVADAVK RFRDAFWPNG ILAETVPRRD KAIRMRTRVA GKTKLLEVMP DELKHIIGAE
TTRKGILRVF EMFQHTQLNK RMVYVFLERF LETLFPQNKF HELFNKLHSR SKQMQRYKQR
LHTTQAPSLQ KSLLVSHIRL LMHL
//
