ID R0KPQ9_NOSB1 Unreviewed; 338 AA.
AC R0KPQ9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=RING finger protein 121 {ECO:0000313|EMBL:EOB12172.1};
GN Name=RN121 {ECO:0000313|EMBL:EOB12172.1};
GN ORFNames=NBO_508g0023 {ECO:0000313|EMBL:EOB12172.1};
OS Nosema bombycis (strain CQ1 / CVCC 102059) (Microsporidian parasite)
OS (Pebrine of silkworm).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae; Nosema.
OX NCBI_TaxID=578461 {ECO:0000313|EMBL:EOB12172.1, ECO:0000313|Proteomes:UP000016927};
RN [1] {ECO:0000313|EMBL:EOB12172.1, ECO:0000313|Proteomes:UP000016927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQ1 / CVCC 102059 {ECO:0000313|Proteomes:UP000016927};
RX PubMed=23496955; DOI=10.1186/1471-2164-14-186;
RA Pan G., Xu J., Li T., Xia Q., Liu S.L., Zhang G., Li S., Li C., Liu H.,
RA Yang L., Liu T., Zhang X., Wu Z., Fan W., Dang X., Xiang H., Tao M., Li Y.,
RA Hu J., Li Z., Lin L., Luo J., Geng L., Wang L., Long M., Wan Y., He N.,
RA Zhang Z., Lu C., Keeling P.J., Wang J., Xiang Z., Zhou Z.;
RT "Comparative genomics of parasitic silkworm microsporidia reveal an
RT association between genome expansion and host adaptation.";
RL BMC Genomics 14:186-186(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB909416; EOB12172.1; -; Genomic_DNA.
DR AlphaFoldDB; R0KPQ9; -.
DR STRING; 578461.R0KPQ9; -.
DR EnsemblFungi; EOB12172; EOB12172; NBO_508g0023.
DR VEuPathDB; MicrosporidiaDB:NBO_508g0023; -.
DR HOGENOM; CLU_055016_0_0_1; -.
DR OMA; PYWERTH; -.
DR Proteomes; UP000016927; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR040176; RNF121/RNF175.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13407:SF0; FI05221P; 1.
DR PANTHER; PTHR13407; RNF121 PROTEIN; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000016927};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 246..289
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 338 AA; 39966 MW; 60829671CE82316B CRC64;
MATDDEQKAL NKSQEFNETQ ILKPARELSE ATSNNHDIDN LQTMDHNFNT NHHNFNETHR
PQVIREFYIV KEEPTVFDFI PLFFTFIVYA IMIQTICLAV KKINKPLYDN VIRVLLIIFP
PLLLMIAKSY LFTIIWFFYA SFMIYKYFKI KKKPIGKEVP RETYDLFKKL FVLTNLGIGI
CQGMLFISFF IFPNNIVQFF LLFVFFLYFG LLSREIILFF SETMAINTGF YSKEGVPGRT
NNNSLCMICT KVFDNTETIH TLVCSHSFHE VCIKGWCMIA KKGFCPYCKK GVDMNSIPTE
VWYKTEVWFY PMINMLKNII IFCMFMCCII MYNYYTFN
//
