ID R0LFJ6_ANAPL Unreviewed; 363 AA.
AC R0LFJ6;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 08-NOV-2023, entry version 40.
DE SubName: Full=SH3 and cysteine-rich domain-containing protein {ECO:0000313|EMBL:EOA99052.1};
DE Flags: Fragment;
GN ORFNames=Anapl_14107 {ECO:0000313|EMBL:EOA99052.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOA99052.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004278}.
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DR EMBL; KB743391; EOA99052.1; -; Genomic_DNA.
DR AlphaFoldDB; R0LFJ6; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20880; C1_Stac1; 1.
DR CDD; cd11833; SH3_Stac_1; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR039688; STAC1/2/3.
DR InterPro; IPR035508; STAC1_SH3.
DR PANTHER; PTHR15135:SF3; SH3 AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15135; STAC; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF16664; STAC2_u1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR PRINTS; PR01887; SPECTRNALPHA.
DR SMART; SM00109; C1; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50002; SH3; 2.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 70..122
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 246..305
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 308..363
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 43..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOA99052.1"
FT NON_TER 363
FT /evidence="ECO:0000313|EMBL:EOA99052.1"
SQ SEQUENCE 363 AA; 41024 MW; B52D8F815584F6A0 CRC64;
QLQKLKRSLS FKTKSLRSKS ADNFFQRTNS DVKLQVDLMP EVSTSTGQLP SSDSQASSPA
RAQQLPENKA HIFQEHIFKK PTFCDVCNHM IVGTNAKHGL RCKACKMSIH HKCADSIGQQ
RCMGKLPKGF RRYYSSPLLI HEQFGCIKEV MPIACGNKVD PVYETLRFGT SLAQKTKKGS
SGSGSDSPNR NSTADLAEVP EEADSSLDIS RKRSNSVFTY SENGTEHFGE EPKNIHSPGP
FYKSTLQMNT YVALYKFVPQ ENEDLEMRPG DMITLLEDSN EDWWKGKIDD RTGFFPANFV
QRVQHDEKIY RCIRTFIGCK EQGQITLKEN QICVTSEKEH DGFIKVYSGK KKGFVPIDIL
ENI
//
