ID R0LYD9_ANAPL Unreviewed; 1660 AA.
AC R0LYD9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Plexin-D1 {ECO:0000313|EMBL:EOB06840.1};
DE Flags: Fragment;
GN ORFNames=Anapl_06420 {ECO:0000313|EMBL:EOB06840.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB06840.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; KB742579; EOB06840.1; -; Genomic_DNA.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd12788; RasGAP_plexin_D1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF7; PLEXIN-D1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01833; TIG; 3.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 3.
DR SMART; SM00423; PSI; 3.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1006..1028
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..278
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOB06840.1"
FT NON_TER 1660
FT /evidence="ECO:0000313|EMBL:EOB06840.1"
SQ SEQUENCE 1660 AA; 186466 MW; 6160549056C6A37D CRC64;
KARHKLSFVR AFLQRGAAPP ARRPYAYLAL NSEANAGDKE SPSHSLLARI CLGDAAEATL
NGSGETKKLT ESYIQLGLXS GCNTLADKRM IVCTNCWQHW EGSAMNRLCL GRDSVADSGF
CRTQKGACAF CFHNATESAG HHLSLCPFYY GACGIFPLLI NLAQNGHVCC LAVGQLQPEQ
LDCGAAHLQH PLAIXAVAVA SVNNYTVVFL GTASGGLLKA MSGVFSLQIN LDSAMKVVSR
RSISVAYGEP VHPIMQFDPS DSTFLYLMTS YQMTRVKVAV CNQYSTCAEC LAAADAYCGW
CTMETRCSLQ HECTNFTETN FWASASEGVQ QCPSMTILEP EINIEKEKPA LIIQINGTIP
NLNGTNISCD YGNNIHTVAR VAGDYANQFI YCSLLPREKY PAFPDNQDHV IVETALRVNS
KNIIRANFTI YDCKRTGNIY PKRACTSCLS TKWKCYWCPS TYMCVSNRSQ CEDTLQMKKK
IDCPRIVPVS LDPMPTGTSR DITISLANAT FSKETALECH FGTDRTFEAR WVNSSAVECV
HVLLHTSEKS HLFPVNLQLK DRPDRFIDSP ETMTVEVYNC GTGSADCSQC LGREDLGHRC
VWSESSSSCR LSTEFPQISD MCPAPEIKKI EPLRGPLEGG TLLTIRGRNL GRRFSDIRGA
VRIGSVPCAP LPHRYXIVCQ TGEALEVFSD VVTVNVSREG KSKERYSYVL PVVQSIAPPN
GPKAGGTRVT IRGSRLDVGS ELRVLVNGSR QCTDLSRNDS TITCTMPSAE LTTAVRVCVQ
FENRSCASYN ITFKYEKNPI ITDINPKKSQ ISGGRIITLE GRGFELVQNV SMMVRGIGRE
QTSCKVHNDT VITCPSPAAS NITAGSKPAP VDFYLNGRLY TDDRPALDEE MYPEEALHIS
KFSLEYYADP QFFTAKKEKW IKHHPGEPLT LVIHKEPDNL GLESNEYQVK IGLISCEIQI
VSDKVIHCSV NESLSTSERQ LPVTIQVGKF NYTIAMLHLG GGETAIIVSI VICSILLVLS
VVALFVFCTK SRRAERYWQK TLLQMEEMES QIREEIRKGF AELQTDMTDL TKELNRSQGI
PFLEYKHFVT RTFFPKCSSL YEECYILPSQ QLSSQVGSQV QETHPLLVGE WKIPENCRPN
MEEGISLFST LLNNKHFLIV FVHALEQQKD FAVRDRCNLA SLLTIALHGK LEYYTSIMKD
LLVDLIDASA SKNPKLMLRR TESVVEKMLT NWMSICMYSY LRETVGEPFF LLICAIKQQI
NKGSIDAITG KARYTLNEEW LLRENIEAKP RNLNVSFQGC GMDSLSVRAM DTDTLSQVKE
KILEAFCKNV PYSQWPRVED VDLEWFATST DSYILRDLDD TSVVEDGRKK LNTLAHYKIP
EGASLAMSLS DKKDATLSRV KDLDTEKYFH LVLPTDESVE HKKSHRQSHR KKVLPEIYLT
RLLSTKGTLQ KFLDDLFKAI LSIRDDKPPV AVKYFFDFLE EQAEKRGITD PDTMHIWKTN
SLPLRFWVNI LKNPQFVFDI DKTDHIDACL SVIAQAFIDA CSLSDLQLGK DSPTNKLLYA
KEIPEYRKIV QRYYKQIHDM PPLSEQEMNA HLAEESRKYR NEFNTNVAMA EIYKYAKRYR
SQIVAALDAN PTTKRTQLQH KFEQVIALME DNIYECCSEA
//
