ID R0M3G1_ANAPL Unreviewed; 820 AA.
AC R0M3G1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 {ECO:0000313|EMBL:EOB08650.1};
DE Flags: Fragment;
GN ORFNames=Anapl_01830 {ECO:0000313|EMBL:EOB08650.1};
OS Anas platyrhynchos (Mallard) (Anas boschas).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC Anatinae; Anas.
OX NCBI_TaxID=8839 {ECO:0000313|EMBL:EOB08650.1, ECO:0000313|Proteomes:UP000296049};
RN [1] {ECO:0000313|Proteomes:UP000296049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23749191; DOI=10.1038/ng.2657;
RA Huang Y., Li Y., Burt D.W., Chen H., Zhang Y., Qian W., Kim H., Gan S.,
RA Zhao Y., Li J., Yi K., Feng H., Zhu P., Li B., Liu Q., Fairley S.,
RA Magor K.E., Du Z., Hu X., Goodman L., Tafer H., Vignal A., Lee T.,
RA Kim K.W., Sheng Z., An Y., Searle S., Herrero J., Groenen M.A.,
RA Crooijmans R.P., Faraut T., Cai Q., Webster R.G., Aldridge J.R.,
RA Warren W.C., Bartschat S., Kehr S., Marz M., Stadler P.F., Smith J.,
RA Kraus R.H., Zhao Y., Ren L., Fei J., Morisson M., Kaiser P., Griffin D.K.,
RA Rao M., Pitel F., Wang J., Li N.;
RT "The duck genome and transcriptome provide insight into an avian influenza
RT virus reservoir species.";
RL Nat. Genet. 45:776-783(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KB742432; EOB08650.1; -; Genomic_DNA.
DR AlphaFoldDB; R0M3G1; -.
DR Proteomes; UP000296049; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd16018; Enpp; 1.
DR CDD; cd00091; NUC; 1.
DR Gene3D; 4.10.410.20; -; 2.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease.
DR InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR InterPro; IPR020821; Extracellular_endonuc_su_A.
DR InterPro; IPR044925; His-Me_finger_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR10151:SF107; ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 3; 1.
DR Pfam; PF01223; Endonuclease_NS; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR Pfam; PF01033; Somatomedin_B; 2.
DR SMART; SM00892; Endonuclease_NS; 1.
DR SMART; SM00477; NUC; 1.
DR SMART; SM00201; SO; 2.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR SUPFAM; SSF54060; His-Me finger endonucleases; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 2.
DR PROSITE; PS00524; SMB_1; 2.
DR PROSITE; PS50958; SMB_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000296049};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 1..42
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 43..87
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOB08650.1"
FT NON_TER 820
FT /evidence="ECO:0000313|EMBL:EOB08650.1"
SQ SEQUENCE 820 AA; 93873 MW; 3AC29CB6FB6F5EB9 CRC64;
VSCRHKCNEP YRKEVAGCQC DSGCKERQDC CWDYEDACVE PTQSWRCTNF RCGEKRLPGS
YCSCSDDCLQ NKDCCVNYNS ICKGEIPWVE EPCTPLETPQ CPAGFDVPPL ILFSMDGFRA
EYLQTWGSLL PNIEKLKTCG THSKYMRAAY PTKTFPNHYT IVTGLYPESH GIIDNSMYDV
DLNRHFSLSG TEKFQPEWWK GQPMWLTAMY QGLKAGTFFW PGSDVPINGT YPDLYKMYNN
SVTYEERISG ILKWLDYNKS ERPDFYTLYV EEPDSSGHSF GPVSAGVIKA LQLADQTLGM
LMEGLKQRNL HNCVNLIVLA DHGMDKTYCS QLEYMTDYFK QVNFYIYAGP AARIRANKVP
QDYYTFDSEG IVKNLTCKRS PQHFKPYLTP NLPKRFHYAN NIRIDKVHLL VDRQWLAVRD
NSYTFCDVGN HGYDNEFKSM EAIFLGYGPS FKEKIEVDAF ENIEVYNLMC DLLHITPAPN
NGTHGSLNHL LKKPFYNPSH AKEESSPLSC PVSSLVPADD LGCTCNITDL SVVNKRLNLT
TDEIKNVTSY HLPYGRPKVL QKNNIYCLLP HYQYVSGYSH DIWMPLWTAY TVNKPESTSS
LPPTGSDCLR ADVRIPVAHS QNCSDYPEGL NLTYGFLYPP NFSSSTLEQY DALLTSNIVP
MYEAFRDIWD YFHNVLLQKY ARERNGVNVI SGPVFDYNYD GHFDTPDEIT QHVNNTQIPI
PTHYFVVLTS CKNISYTPLN CTGSLDVLSF IIPHQPDNTE SCAENRLPSE WVEERVQAHS
ARVRDVELLT GLDFYQERQE SVSEILQLKT YLPTFETEIN
//
