ID R1BJ59_EMIHU Unreviewed; 1513 AA.
AC R1BJ59;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=EMIHUDRAFT_448382 {ECO:0000313|EMBL:EOD09487.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD09487.1};
RN [1] {ECO:0000313|EMBL:EOD09487.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD09487.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD09487}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB868684; EOD09487.1; -; Genomic_DNA.
DR RefSeq; XP_005761916.1; XM_005761859.1.
DR STRING; 2903.R1BJ59; -.
DR PaxDb; 2903-EOD09487; -.
DR EnsemblProtists; EOD09487; EOD09487; EMIHUDRAFT_448382.
DR GeneID; 17255626; -.
DR KEGG; ehx:EMIHUDRAFT_448382; -.
DR eggNOG; KOG0920; Eukaryota.
DR HOGENOM; CLU_248114_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 670..840
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 933..1108
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 188..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1474..1513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 603..630
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 343..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1513 AA; 162168 MW; A1EFB1FBEE4B4125 CRC64;
MDKGRGSAPD YAIWMDAAEE QALREALHVA QAAQAEVDQQ RGGGGRLLRD ARKLHQVYGQ
LARLGFGKED IEQCLPHMRS DSSLNDALDW ACLHLPEASL PPSFRMATPD AEDGDKELDK
SSLLKKIVSA PAVAKPEGRF LEAKKRAAAF AKKAAGGAAL VRLVPKFETR VAKRRSAVEA
EAKRAVRRKS WRAERQQAKR APTSTNPSAE EEFAVDFGDG SSQDGGARDR TPPPGARGEQ
ALASWLSEEC GIGAPEATAF AAALAADGRT RSKRHLTGRA LASLAASVPI GYDSTLALCE
IEETDWPDMV PAHHRDIIKA SAVAAGGIGG GGPGQAGEAE VEVAKRTAAE RGAAERVQRG
AADREAGSES NSAPAVASGG ASGGGGKSKK RSGGSGKKKG GGGGGGNAAA QRAAMLAKYQ
TTSVAKPVVE KAAEREVSAD VPEAAATAAS PGPPPPSATD AAAGVDGVSC ADDDVANGGT
GRYDLSRWSG KTPKTMLLEW FQKMQAPRPK IELESVGRRY RAYVVVVGDT KLELPGDEVF
DKREQAEQAA ATAALYHLFG TGKEKQPLYR MLPPAYRTLW LGWVSNQQTA AAQLEADSAA
AALIERERFV DRLEEEAEAA ERQERREARE VETGSRLQAA HARWVEAAAG CASAAQRASL
PISKLAEQLS TAMASTQVAV LCGETGSGKS TQVPQMLLEE ALASGAGGTT SILCTQPRRI
AATSLARRVA SERGEQVGGR GSLVGYQVRL ESKRTESTRL LYCTTGIALR MMLCEKPLEG
ISHVVVDEVH ERDTQTDLLL LLLRELLPLR PDLRVVCMSA TVQAELFSSY FGGCPVLTAQ
GRSYPVTDTF LEDILATTGH VLPPDSPCRV SDHGTWNKAT FNLHRGGQAS TQEWKEAGAA
TNPDYDEGRY AAYPPGVHAV LSQLNESAIN HDLIMELVDY IDLNLGDGAV LVFLPGFADI
STLYNTMSSS RRFGDRAAFR VLPLHSSLSP AEQSAVFDVM PTGVRKVVLA TNIAETSITI
DDAVFVIDSG RAKSAMFDER KQMRRLVDVW ISQAEARQRA GRAGRVRAGH AFKLYTRQRY
TQSMLPARVP EMLRGPLQEL CLQLRLAPLL ESYELRAAFA RALDPPKAAT VEAAIIALQR
SNALDADEAL TPLGRHLAAL PVEICIGRLM LYGALFSCAD PILLIAAALS DRSPFLQPLA
RRDEAKAAQV CFNRDESDHL AAVDAYQKWM HVKRTEGNGG AKRFCDRHFL AERALVGMGE
AADQFWGNLA DLGLLPELRR LGEADKQAAR RSANRHADSP LLLKAVLAAG LFPNVLLVSP
GRARPSLSQQ KQSVSIHPSS FNHMASSFTT SYLVFHEKVK TSKIVVHDVT AVTALDLLLL
GGEIKVLHAQ HRVVIDNWID LTISPRVAVL FKALRHQMMS LMRRRIADAG GARDGGHAPQ
AAVLEAVVEM VKRGTVAAEI NPEAIKERAI AAREREQQAK PSGRGGGNTK PELGKGKGGG
RGGRRQLGSL VYT
//
