ID R1CQC7_EMIHU Unreviewed; 1246 AA.
AC R1CQC7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=CUB domain-containing protein {ECO:0000259|PROSITE:PS01180};
GN ORFNames=EMIHUDRAFT_100901 {ECO:0000313|EMBL:EOD25193.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD25193.1};
RN [1] {ECO:0000313|EMBL:EOD25193.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD25193.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD25193}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB865350; EOD25193.1; -; Genomic_DNA.
DR RefSeq; XP_005777622.1; XM_005777565.1.
DR PaxDb; 2903-EOD25193; -.
DR EnsemblProtists; EOD25193; EOD25193; EMIHUDRAFT_100901.
DR GeneID; 17270739; -.
DR KEGG; ehx:EMIHUDRAFT_100901; -.
DR eggNOG; ENOG502QSG1; Eukaryota.
DR HOGENOM; CLU_002103_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR Pfam; PF00431; CUB; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 604..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..721
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 774..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 849..874
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..333
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT REGION 354..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1227..1246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..390
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1246 AA; 132294 MW; AAC996CE427A291A CRC64;
MLAVALLAAP SNAASRPRPR RGEALIGTRN RTDFSIKLST DAPAPALAAS ASRKPDKATE
LLLHQDVLGR EWALFDVLPD ATFHPTFSFP FNLSKFSGAN SRAAGPTTFK PIGAAADAAL
ASFGETTGAA MTEIGKTYPI TSKLNIGSYA ELLTTATLLF LHPCAAVLAL LLAACLEPLL
RGQVKKKRVE GRSHAAISVP LLSSTRALRV GIVILFCLQG VCGTPAAPLQ PVNVSSPCSL
TDGGSCAASP NYPNSYGNNE ECTISGVPPV GLETVAFEVE AGNGCPYDYL TVNGTKYCGT
SGPQGAVAED GVIEWFSDGS VVRSGWKARP WSLSLPPSLS SLMPSSLCRQ ICWATRPPSP
PSPPPSPSPP PSPPPSPPAS PLPPPPPLSP FVAAESEAEL RSLIQYAAVT AADVSIYLPP
SDVEIIDSAV TDCAATGSSP DGYGGVVFAV SSGSVSISGS TVTGCSAGWD GGVVYAWYSG
AVSITRSNVR DCYAGYEGGV VFANRSDSLS IAGVDFIDNV AVDSTGSVLY LRSVEQTSIS
NASFTGNTGI TVKIMFGFYQ ISTVLSSTYS ARLPPEYTDW TDKLANAISI DWSGFYLPEQ
CLGYALRLLA IALSPVALIA LLMIAGISLR LHCWRAAPAP RERPWYAEAA LGLLDLTPAG
LAYTISPPNE PLRQVSYMRQ DASVECGSDD HGPIKNLAIG FIVLWPAGSL VLFTSLLAAC
YKPLQAKTPN ALTRATAFLH REYEKTWYWW EAVELARKLV LTGFVLLIPE ERAFVRLVVA
TLICSCYAVA LAVVRPYKRV EDNVVAVATS LVLLLLFLGA NWSTIFLSIE ERHPDTAEAA
AVLGFGELNV IVDSMIILVA VVLAFFLVGA IVAARRVAKV PTIRLVSTKQ PPEMSIGTGI
TWHLFNSHIW STGQDAVKVI KGELQQLLPD IKNCLREVRS SLEKDKPLVL VQEADPAKGG
GTLQALRDEC PEDLQPAIFD KDWPLTIWYR IDEFQLISLK IIAEAPPAAA SRSAAVLLCS
PNFLDNTTLP LCVSGELESQ SLAFSKPCTL WASPANPGAA ELACELARAF PGLTVSTVAD
VGSSASARPS TALRGLARRT RRAGDVTHML LYLNQNTWLE DDGERLAEQV KQAREDKLKL
VMAHENDPAL GGCQFSRSSS PADSTRTWQN RASPVSLVLL AKSLGATPAR SRADLLVSGS
VAEGSTSLVK RSLGGFSRVF AKMSSRSSAE ARDVSGGEAS SVQRQV
//
