ID R1E7K4_EMIHU Unreviewed; 857 AA.
AC R1E7K4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=AB hydrolase-1 domain-containing protein {ECO:0000259|Pfam:PF00561};
GN ORFNames=EMIHUDRAFT_118271 {ECO:0000313|EMBL:EOD18966.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD18966.1};
RN [1] {ECO:0000313|EMBL:EOD18966.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD18966.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD18966}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB866386; EOD18966.1; -; Genomic_DNA.
DR RefSeq; XP_005771395.1; XM_005771338.1.
DR PaxDb; 2903-EOD18966; -.
DR EnsemblProtists; EOD18966; EOD18966; EMIHUDRAFT_118271.
DR GeneID; 17264512; -.
DR KEGG; ehx:EMIHUDRAFT_118271; -.
DR eggNOG; ENOG502T06M; Eukaryota.
DR HOGENOM; CLU_333568_0_0_1; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR13037; FORMIN; 1.
DR PANTHER; PTHR13037:SF24; NEURAL WISKOTT-ALDRICH SYNDROME PROTEIN; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..857
FT /note="AB hydrolase-1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014592046"
FT TRANSMEM 138..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 301..382
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 30..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..106
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 90441 MW; 1B2E9080879A2DEB CRC64;
MPLAAFGVFA FLAVAAAVVV SLRRNSHKAA HQPLLSPPPS PPPADGPLIA GTSSDSLQSE
SARPPPPPPP AKTAMCNMDL RVLSCGRPGP PPPPYPGPPG PVGPAGPAGP RGYQGVAGED
GKTGPEGPPG PPRRALNVMW LVIIFSSLIS VVAIILAAIC FSSDSCGSPS PPPSPVPDPC
PCTPGADPAA LIACGECCIA HPGCGRCSDF CVAQSPPPPP PPPPPPPPPL PPKWSVCDPD
PDLLRWDSYL QRPNGGTARF GWLKVYAKLQ NAAMSECRTR PEYILGTNDA RGTMTYQDFV
GTFDLAQDMD IFRAAVGAET LSVYGISYGT EVGASYATMF PERVDKLVLD GNVAVSNELY
EYAELLALSY EQVWNGLAAA CNDDFFVKNT TDLSADDLCA AAPYPTDKIY SIIRNQTDQS
FASFVLNQME GGGDGGEGRG GGGGGGGENG GTEFVSATQA RPGGIPFGQL NNNFAQHPDP
AKPLVIPVDS TVVGSTLRFI PWSVVGNPAF LQLPPPPPGM QPSWVQIPQW VAISALLPFS
EPEPAVATHF DRLSVLRLAV LAAAWRRILG ALSDLGVFST VHVDEDAFRT VCIQALHSRQ
IPVPELYLQW GDLGYSEAIT PLGPAPSAEA KAVDFLQYAT VGALCDPTAD VPFAALSDMT
RCLGPVFTAA ARVDPMGSAV VGAASLAAAA GHITPRASDG HPSLLARHVL SMLKTTRSSF
PACLRTNSFQ NYSAEVETRA EYVGGTTVAR DRVAEQRCSR AIAAKAPTLD SLLRKPAKAW
AARGGDRWPS PVGLMARNNY QDFVELNVST CGATDATAEL RERRQLARRS IRAFGPRDLW
RPSQRQAWAL PKRIAGN
//
