ID R1EVY4_EMIHU Unreviewed; 428 AA.
AC R1EVY4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Growth arrest-specific protein 8 domain-containing protein {ECO:0000259|Pfam:PF13851};
DE Flags: Fragment;
GN ORFNames=EMIHUDRAFT_73993 {ECO:0000313|EMBL:EOD24979.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD24979.1};
RN [1] {ECO:0000313|EMBL:EOD24979.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD24979.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD24979}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the DRC4 family.
CC {ECO:0000256|ARBA:ARBA00009859}.
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DR EMBL; KB865357; EOD24979.1; -; Genomic_DNA.
DR RefSeq; XP_005777408.1; XM_005777351.1.
DR STRING; 2903.R1EVY4; -.
DR PaxDb; 2903-EOD24979; -.
DR EnsemblProtists; EOD24979; EOD24979; EMIHUDRAFT_73993.
DR GeneID; 17270525; -.
DR KEGG; ehx:EMIHUDRAFT_73993; -.
DR eggNOG; ENOG502QQDA; Eukaryota.
DR HOGENOM; CLU_045343_0_0_1; -.
DR OMA; MKHLQYE; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0048870; P:cell motility; IEA:InterPro.
DR InterPro; IPR039308; GAS8.
DR InterPro; IPR025593; GAS8_dom.
DR PANTHER; PTHR31543; DYNEIN REGULATORY COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR31543:SF0; DYNEIN REGULATORY COMPLEX SUBUNIT 4; 1.
DR Pfam; PF13851; GAS; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827}.
FT DOMAIN 174..374
FT /note="Growth arrest-specific protein 8"
FT /evidence="ECO:0000259|Pfam:PF13851"
FT COILED 88..182
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EOD24979.1"
SQ SEQUENCE 428 AA; 49009 MW; EC6A882A74A85518 CRC64;
QVATFWEICK KELEDRKAEG RNKEREMEEL EERHQVEVKV YKQKARIPSS PPLRVKHLLY
EHQNNVAQLK EAGELALKLQ LGEHHSNESE SKKDKRSLKL ELKELELAHE DAIRELRLEN
DKNITKLRQQ YEREVTELSS KYEKKMKLLR DDLELRRKVE ILEIEERKNN HINELMKKHE
KAFGEIKNYY NDITHNNLDL IRSLKEEATV GRASCAQVAN EKLMYEIAQE NKKLSEPLSR
ALKEAHGAGA RCCGEAPDLS AVPRHPTQVE GLRKELANYS KDKVLGQRHS HVEKERDALY
DKFEATIYDV QQKSGFKNIL LERKLATVNE TLEQKDAQLS EVLSAANLDP AVLGSVSKRL
DDVLAGKNGT IKELQYELAR VTKAHNDVIR TYEARLEELG VPTATMGFRP RQLATVTATG
AAGLVTAT
//
