ID R1G128_EMIHU Unreviewed; 1063 AA.
AC R1G128;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Aminotransferase class V domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EMIHUDRAFT_462145 {ECO:0000313|EMBL:EOD39489.1};
OS Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi).
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Isochrysidales;
OC Noelaerhabdaceae; Emiliania.
OX NCBI_TaxID=2903 {ECO:0000313|EMBL:EOD39489.1};
RN [1] {ECO:0000313|EMBL:EOD39489.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|EMBL:EOD39489.1};
RG DOE Joint Genome Institute;
RA Read B., Kegel J., Klute M., Kuo A., Lefebvre S.C., Maumus F., Mayer C.,
RA Miller J., Allen A., Bidle K., Borodovsky M., Bowler C., Brownlee C.,
RA Claverie J.-M., Cock M., De Vargas C., Elias M., Frickenhaus S.,
RA Gladyshev V.N., Gonzalez K., Guda C., Hadaegh A., Herman E.,
RA Iglesias-Rodriguez D., Jones B., Lawson T., Leese F., Lin Y.-C.,
RA Lindquist E., Lobanov A., Lucas S., Malik S.-H.B., Marsh M.E., Mock T.,
RA Monier A., Moreau H., Mueller-Roeber B., Napier J., Ogata H., Parker M.,
RA Probert I., Quesneville H., Raines C., Rensing S., Riano-Pachon D.M.,
RA Richier S., Rokitta S., Salamov A., Sarno A.F., Schmutz J., Schroeder D.,
RA Shiraiwa Y., Soanes D.M., Valentin K., Van Der Giezen M., Van Der Peer Y.,
RA Vardi A., Verret F., Von Dassow P., Wheeler G., Williams B., Wilson W.,
RA Wolfe G., Wurch L.L., Young J., Dacks J.B., Delwiche C.F., Dyhrman S.,
RA Glockner G., John U., Richards T., Worden A.Z., Zhang X., Grigoriev I.V.;
RT "Genome variability drives Emilianias global distribution.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000013827}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP1516 {ECO:0000313|Proteomes:UP000013827};
RX PubMed=23760476; DOI=10.1038/nature12221;
RA Read B.A., Kegel J., Klute M.J., Kuo A., Lefebvre S.C., Maumus F.,
RA Mayer C., Miller J., Monier A., Salamov A., Young J., Aguilar M.,
RA Claverie J.M., Frickenhaus S., Gonzalez K., Herman E.K., Lin Y.C.,
RA Napier J., Ogata H., Sarno A.F., Shmutz J., Schroeder D., de Vargas C.,
RA Verret F., von Dassow P., Valentin K., Van de Peer Y., Wheeler G.,
RA Dacks J.B., Delwiche C.F., Dyhrman S.T., Glockner G., John U., Richards T.,
RA Worden A.Z., Zhang X., Grigoriev I.V., Allen A.E., Bidle K., Borodovsky M.,
RA Bowler C., Brownlee C., Cock J.M., Elias M., Gladyshev V.N., Groth M.,
RA Guda C., Hadaegh A., Iglesias-Rodriguez M.D., Jenkins J., Jones B.M.,
RA Lawson T., Leese F., Lindquist E., Lobanov A., Lomsadze A., Malik S.B.,
RA Marsh M.E., Mackinder L., Mock T., Mueller-Roeber B., Pagarete A.,
RA Parker M., Probert I., Quesneville H., Raines C., Rensing S.A.,
RA Riano-Pachon D.M., Richier S., Rokitta S., Shiraiwa Y., Soanes D.M.,
RA van der Giezen M., Wahlund T.M., Williams B., Wilson W., Wolfe G.,
RA Wurch L.L.;
RT "Pan genome of the phytoplankton Emiliania underpins its global
RT distribution.";
RL Nature 499:209-213(2013).
RN [3] {ECO:0000313|EnsemblProtists:EOD39489}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; KB863646; EOD39489.1; -; Genomic_DNA.
DR RefSeq; XP_005791918.1; XM_005791861.1.
DR STRING; 2903.R1G128; -.
DR PaxDb; 2903-EOD39489; -.
DR EnsemblProtists; EOD39489; EOD39489; EMIHUDRAFT_462145.
DR GeneID; 17284760; -.
DR KEGG; ehx:EMIHUDRAFT_462145; -.
DR eggNOG; KOG2840; Eukaryota.
DR HOGENOM; CLU_003433_9_1_1; -.
DR OMA; CATVDPQ; -.
DR Proteomes; UP000013827; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd01993; Alpha_ANH_like_II; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR011063; TilS/TtcA_N.
DR PANTHER; PTHR43686; SULFURTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR43686:SF1; TRNA-CYTIDINE(32) 2-SULFURTRANSFERASE; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR Pfam; PF01171; ATP_bind_3; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000013827};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 31..272
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
FT DOMAIN 665..834
FT /note="tRNA(Ile)-lysidine/2-thiocytidine synthase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01171"
FT REGION 598..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 989..1027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1063 AA; 111518 MW; C0FF04504920C268 CRC64;
MSANLLEYIR DSELGANLCS QTPFGTRALI YADYTASGRA LSFIEEFVRE AILPTYGNTH
TATTKTGRQT SDFVAEARAM IKTYLRCNDR GKTNADRLLF AGAGATAGAN RLVSLLGLVA
PTPEAREAAA ARPVSERPLV LVGPYEHHSN LLPWRDSSAD VVAVPEDAEQ GGADLGALEE
ALLEAKADGR PLVVGAFSAA SNVTGIVARV DDITALLHTH GAHSPSRRAM NPPHEDAARA
ALLAKDALFF SPHKLAGGPQ ASGILVYKKS LARRGVSSAR GRRGTRLGHS RPVSGEAVGA
AAIAEADAAL LAATRAAWGA HPRLAILGHP TARRLPIFAI AIRAFDPGGG GGEGEAATRP
LLLHHNFVVA LLNDLFGIQA RGGCMCAGPY SQALLGIDSA LSAALQAQLV KKEDNEVLRP
GYTRVSLPYF ADAATVRYVL DALLFVAEHG WKLLPQYTHV HQKRPARAWL GSVSYDGGRM
AWGGSAGAPA QLRADERGEA AAEARYASAL AEAHAVAKVA SSELRRNTGA PLAGQSLGEL
LPPEAAHLRW FVLPAEAAAM HKGRLPAARA PFAPPAFAQA DAARALAPHS VAAAAGGGEA
AAAGQPGAGE AKERVGGRGN AGKKKKGRKG GGGGGDGWVE PDKKLSNKVF RAVLQHGMLR
PGDRVLVGLS GGKDSLCMLH VLRALQKRTP FQWDLGACTV DPKADGFDPS PLVPYLEGLG
IPYFYEAHNL MALAEPCMAK EGNRVSICSF CSRMKRGVLY ATARREGYNV LAMAQHLDDL
AESFFMSALH NGALRSMKTH YLIDAADLRV IRPLAYVREA EAEAFAESNH LPVVSETCPA
CFEAPKERYR VKCLLATQEA LFPALFQSLL KTILPLTEPL VEDVVRLRRE AYGRAAGPPH
VPPPMPPPAE GALAEMEAAA RKAHEPAGVY DARALWRAAL AVSRQRLGGS AKGRGGEGDG
DGAAAAAAAA ALEEEDLSAS WFGGHLDENG NFTRGGGGGG AQTQPRKEGS RWGEGRGAPA
AGERGVASGE VAPGGSWQLL ALGVAWSLGC IAWASVSKAR AGR
//
