ID   R1GB75_9PSEU            Unreviewed;       960 AA.
AC   R1GB75;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=P/Homo B domain-containing protein {ECO:0000259|PROSITE:PS51829};
GN   ORFNames=H480_10425 {ECO:0000313|EMBL:EOD68617.1};
OS   Amycolatopsis vancoresmycina DSM 44592.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1292037 {ECO:0000313|EMBL:EOD68617.1, ECO:0000313|Proteomes:UP000014139};
RN   [1] {ECO:0000313|EMBL:EOD68617.1, ECO:0000313|Proteomes:UP000014139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44592 {ECO:0000313|EMBL:EOD68617.1,
RC   ECO:0000313|Proteomes:UP000014139};
RA   Kumar S., Kaur N., Kaur C., Raghava G.P.S., Mayilraj S.;
RT   "Draft genome sequence of Amycolatopsis vancoresmycina strain DSM 44592T.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOD68617.1}.
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DR   EMBL; AOUO01000127; EOD68617.1; -; Genomic_DNA.
DR   RefSeq; WP_003071246.1; NZ_AOUO01000127.1.
DR   AlphaFoldDB; R1GB75; -.
DR   PATRIC; fig|1292037.4.peg.1998; -.
DR   eggNOG; COG1361; Bacteria.
DR   eggNOG; COG4935; Bacteria.
DR   OrthoDB; 9813435at2; -.
DR   Proteomes; UP000014139; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd05562; Peptidases_S53_like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR034075; Glr3161-like_dom.
DR   InterPro; IPR002884; P_dom.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   PANTHER; PTHR42884:SF14; NEUROENDOCRINE CONVERTASE 1; 1.
DR   PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR   Pfam; PF01483; P_proprotein; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51829; P_HOMO_B; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..960
FT                   /note="P/Homo B domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004360360"
FT   DOMAIN          771..939
FT                   /note="P/Homo B"
FT                   /evidence="ECO:0000259|PROSITE:PS51829"
FT   REGION          148..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          512..544
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   960 AA;  96934 MW;  ADCDE6BFFAAB5E9A CRC64;
     MLTAGAAALL AALGLVSPPV AGAAPASGPD TFSETAQLQI AALQAVKAGR TATESKVDSK
     LLVAEKGLGK QLNALQSGVS DGGTVVVDIR ASKVSPDLIA GLTKAGAGIR AVSDRYASVR
     AELPVAKVSE IAARDDVKRV EQADQAMTAR ELATPATTPG KSETRTETKQ QKADRIAGEL
     QKAVAAKSQR SAVAAATLTS EGDRAHNADI ARQQFGVTGV GVKACALSDG VDSLAASQAR
     GELPPDVDVI AGQEGDGDEG TAMLEIIHDL APRAALGFAS AFNSDASFAD NIRKLRFQSH
     CDVIVDDVIY FKESPFQDWI IAQAVNDVTA DGALYFSSAG NEGNVASGTA GHWEGDFVDS
     GKAIGKFAGT AHNFAGAAGT QIYEPISNAS SAGVPVTLHW SDPLGASSND YDLYLLNSAG
     AVVSFSQNVQ DGTQDPYEIL QTPTFGGTGL RLAIVKFSGQ NRYLSLSALR GRFSDSADGL
     KAYNTPGVTV GHSAARDAFS VAAAPAAAAF GRPLEPGDPA NPAGPFPGSF SGATKAERFT
     SDGPRRVFYE ANGTPITPGN VSSTGGEVRN KPEITAADGV QTSVTGFNPF FGTSAAAPHA
     AAIAALVLSG NPGLPPAEVR EALINTAIDI EKPGRDNFTG SGVILADKVL AYTGASPQPL
     AVAKQPTVTP ADGGSALDPG DTAKVTLPVT NDGDGTAVST SVVLTSPTPG VTVAPRAKSY
     GTISPGQTGV NDFTITVPAS QQLGVPVVLN ARVTFAGAHS PTTSTFSLPV GTPSPVAKDF
     AYTGAPVAIP DNSPVGASVT IPVTGVGRAS KVTFSVDGTS CSTDPASTTV GLNHSYVGDL
     VGTLTAPSGA KATVFQRNGG SGKNLCQVVF ADNAATAFST VTSSNAPFTG SYRPTQALTG
     NLAGAAADGT WTFSVVDAAA SDTGSIRAVA LHINGFVQPP AAGAPSNVRG VTNNGPVHPL
//